Propranolol for Treating Fibromyalgia Pain

Fibromyalgia Pain Clinical Trial

Official title: Propranolol for Treating Fibromyalgia Pain: Pilot Study

Status Terminated

Clinical Trial Summary

The purpose of the study to evaluate the feasibility of using low dose propranolol for people with fibromyalgia.

Clinical Trial Description

The main purpose of this study is to collect pilot feasibility study data for the use of low dose propranolol for helping treat fibromyalgia. The investigators plan to compare 20mg twice a day dosage of propranolol and 10mg twice a day dosage of propranolol to placebo. The design is a 3 arm, double blind randomized control trial. The investigators will also test ECG and respiratory assessment as a part of the safety screening and the feasible assessment of respiratory sinus arrhythmia.

Propranolol is not indicated to treat pain. However, the previous studies showed that low dose propranolol can re-regulate the adrenergic dysfunction and reduce pain in people with chronic musculoskeletal pain. However, the investigators are not aiming to develop a new indication of the drug. ;

Related Conditions & MeSH terms

• Fibromyalgia
• Fibromyalgia Pain
• Myofascial Pain Syndromes

• NCT number: NCT03029845
• Study type: Interventional
• Source: University of Utah
• Status: Terminated
• Phase: Phase 1
• Start date: January 2017
• Completion date: July 2018