Fever of Unknown Origin Clinical Trial
Official title:
Inflammatory Markers in Patient of FUO With Excess-heat Syndrome and the Influence of Compound Qingre Granule on the Inflammatory Markers
The purpose of this study is to observe inflammatory markers like TNF (tumor necrosis factor), IL-1 (interleukin-1), IL-6 (interleukin-6),TREM-1 (triggering receptor expressed on myeloid cells-1), etc, in patient of FUO with excess-heat syndrome and the influence of Compound Qingre Granule on the inflammatory markers.
All the cases will be provided by the Infectious Diseases Department of Beijing Friendship
Hospital.Each patient should sign informed consent. Assessing the accuracy, completeness, or
representativeness of registry data by comparing the data to medical records. After
collecting, sorting and entering the data, reducing the missing value, and then checking
into the database.
The stochastic indicator method will be used to simple random sampling, to ensure the
probabilities of each individuals be given Chinese medicine intervention are
equal.Operations must be standard to reduce errors.
Quality assurance plan: Patient of fever within two weeks, or whose temperature is below
38.5 degree centigrade will be excluded. The registration form includes the following parts:
Name, sex, age, address, phone number, admission time, primary diagnoses and levels of
Inflammatory markers.
Data will be analyzed using the SPSS17.0 (Statistical Product and Service Solutions 17.0)
statistical software. Difference of measurement data will be compared with analysis of
variance,and difference of enumeration data will be compared with rank-sum test.P<0.05 has
statistical significance.
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Observational Model: Cohort, Time Perspective: Retrospective
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