Influence of Heavy Metals Exposure on in Vitro Fertilization (IVF) Outcome

Status Not yet recruiting

Clinical Trial Summary

Exposure to heavy metals may interfere with basic cellular functions, including DNA synthesis.

The aim of the study is to correlate heavy metals concentration in body fluids of reproductive importance and IVF outcome.

Clinical Trial Description

Concentration of heavy metals will be measured in blood, urine, semen fluid and follicular fluid of IVF patients.

Study group: poor prognosis patients: repeated IVF failure, implantation failure, poor ovarian response, low sperm quality (according to WHO criteria) Control group: Good prognosis patients. Normal sperm count. Heavy metals concentrations will be measured using atomic absorption spectrometer, and will be correlated with IVF outcomes: number of mature oocytes obtained, fertilizations, embryos quality, and reproductive outcome post embryo transfer. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Fertilization in Vitro

Clinical Trial Details

NCT number	NCT02971280
Study type	Observational
Source	Rambam Health Care Campus
Contact	Shahar Kol, MD
Phone	97247773232
Email	skol@rambam.health.gov.il
Status	Not yet recruiting
Phase	N/A
Start date	November 2016

View Details

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