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NCT00608010 Clinical Trial

Day 3 Embryo Cryopreservation: Metabolic and Viability Analysis

Fertilization in Vitro Clinical Trial

Official title:
Day 3 Embryo Cryopreservation: Metabolic and Viability Analysis

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00608010
Other study ID # AH-ART-06/13
Secondary ID
Status Completed
Phase N/A
First received January 22, 2008
Last updated February 5, 2008
Start date October 2006

Study information
Verified date January 2008
Source V.K.V. American Hospital, Istanbul
Contact n/a
Is FDA regulated No
Health authority Turkey: Ministry of Health
Study type Interventional

Clinical Trial Summary

Embryo preservation through freezing plays a significant role in human assisted reproduction. It provides an opportunity for patients to have more than one attempt following an ovarian stimulation cycle, thereby decreasing the exposure of patients to exogenous gonadotrophins and improving cumulative pregnancy rates. The purpose of this study is to compare effectiveness of two different freezing methods.

Recruitment information / eligibility
Status Completed
Enrollment 186
Est. completion date
Est. primary completion date January 2007
Accepts healthy volunteers No
Gender Female
Age group 18 Years and older
Eligibility Inclusion Criteria:

- ICSI with own gametes

- Couples who did not wish to cryopreserve their excess embryos for possible transfer in a future cyle

- Donating excess embryos for research purposes

Exclusion Criteria:

- Embryos derived from surgically retrieved spermatozoa

- Blastocysts

- Embryos of low quality (Grade 3 or 4 according to Hardarson)

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Procedure:
• Vitrification
Embryos were vitrified according to a previously described technique
• Slow freezing
Embryos were frozen with slow freezing technique

Locations
Country Name City State
Turkey American Hospital of Istanbul Istanbul

Sponsors (1)
Lead Sponsor Collaborator
V.K.V. American Hospital, Istanbul

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary Blastocyst development rate 3 days after thawing No
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