Fertility Clinical Trial
Official title:
Association Between Euploid Embryo Grade and Maternal Age, a Retrospective Cross-sectional Study
Background: Advanced maternal age (AMA) is associated with a reduction in live birth rate (LBR) after ART cycles. The main reason for this reduction is the lower number of oocytes aspirated, the number of developing embryos and the low number of euploid embryos available for transfer. The impact of age on success rates after the transfer of an euploid embryo has been a matter of discussion, with a recent meta-analysis showing a reduction in LBR after the transfer of an euploid blastocyst to women of AMA (1). There could be many reasons for this reduced LBR but they can be categorized into two broad categories - the uterus (including the mother's health) and the embryo (including the oocyte and the sperm). It is possible that factors associated with reduced embryo quality would manifest in a lower embryo grade.
Objective: To study if there is an association between advanced maternal age and lower embryo grading of euploid embryos. Hypothesis: Advanced maternal age is associated with a lower embryonic grade in euploid embryos. Study Design: This is a retrospective cross-sectional study of euploid embryos from patients who have completed IVF with PGT-A testing at a fertility clinic in The Prelude Network (US sites only). A comparison of embryo grade between different age groups (<35, 40+) will be done after controlling for baseline demographic characteristics. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Withdrawn |
NCT02759705 -
Bladder Exstrophy (FIVES FertIlity Vesical Exstrophy Sexuality)
|
||
Not yet recruiting |
NCT02534857 -
A Study Comparing a Shorter Exposure of Oocyte to Spermatozoa Versus a Standard Incubation on the Live Birth Rate of In-vitro Fertilization Treatment
|
N/A | |
Enrolling by invitation |
NCT01803893 -
Prognostic Value of PIF Detection in Embryo Culture Media Correlation With Pregnancy Outcome
|
N/A | |
Completed |
NCT01888744 -
Preimplantation Genetic Diagnosis (PGD) With Gonadotropin-releasing Hormone (GnRH) Agonist Versus Antagonist
|
Phase 4 | |
Terminated |
NCT01173276 -
Intrauterine Insemination In HIV-Discordant Couples
|
N/A | |
Not yet recruiting |
NCT03680937 -
Methods for Fertility Preservation: Impact of Vitrification on in Vitro Matured Oocytes
|
||
Completed |
NCT03455062 -
Fertility Study of Women Who Received Organ Transplantation
|
N/A | |
Completed |
NCT02736214 -
Reproductive Life Plan-based Counseling With Men
|
N/A | |
Terminated |
NCT01614704 -
Impact of Sequential Chemotherapy on Young Patients Breast Cancer Treated Fertility
|
||
Completed |
NCT01895192 -
Sperm Morphology by High Magnification in Fertility Men
|
N/A | |
Terminated |
NCT01268592 -
Fertility Preservation in Female Cancer Patients
|
N/A | |
Terminated |
NCT01232972 -
Oocyte Cryopreservation
|
N/A | |
Completed |
NCT01012596 -
Creighton Model Effectiveness, Intentions and Behaviors Assessment (CEIBA)
|
||
Completed |
NCT00390754 -
Usefulness of Home Pregnancy Testing
|
N/A | |
Completed |
NCT00231504 -
Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count
|
Phase 1 | |
Completed |
NCT03345264 -
The Find Your PATHS (Pragmatic Assessment of a Tool to Help Survivors) to Sexual Health and Parenthood Study
|
N/A | |
Recruiting |
NCT05414812 -
Intervening on Women's Health for Rural Young Breast Cancer Survivors
|
N/A | |
Active, not recruiting |
NCT02661932 -
Fertility Preservation in Breast Cancer Patients
|
Phase 4 | |
Recruiting |
NCT06172504 -
Ejaculation Frequency and Semen Parameters
|
||
Recruiting |
NCT02878434 -
Fertility Preservation in Young Women With Cancer
|