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Effect of Timing of Oocyte Denudation Before ICSI in an Oocyte Donation Model

Fertility Clinical Trial

Official title:
Effect of Timing of Oocyte Denudation Before ICSI and Its Results in an Oocyte Donation Model: a Cluster Randomized Controlled Clinical Trial

Clinical Trial Summary

Analyze the effect of preincubation time of oocyte on the results of ICSI in a oocyte donation model.

Clinical Trial Description

There is an intense communication inside the follicular structure. Bidirectional information between the oocyte and the granulosa cells is needed for a normal follicular development and oocyte competence. There are conflicting results on the effect of pre-incubation time in ICSI. It is not clear the proper time to denudate the oocyte from the somatic cells prior to ICSI, and some authors describe a negative impact of the premature cummulus removal on the ICSI results. The aim of this study is to investigate wheter a preincubation time between oocyte retireval and injection has any effect on the ICSI ( intracytoplasmatic sperm injection) results . ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03121924
Study type Interventional
Source Hospital Italiano de Buenos Aires
Contact
Status Completed
Phase N/A
Start date December 1, 2015
Completion date August 1, 2019
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