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Clinical Trial Summary

The influence of thyroid autoantibodies on thyroid function in pregnancy after fertility treatment is not well known.

The objectives of the present study are:

1. To monitor the course of thyroid function during pregnancy and to compare between women with and without thyroid autoantibodies.

2. Compare pregnancy outcome between women with and without thyroid antibodies


Clinical Trial Description

Thyroid autoantibodies and / or abnormal thyroid function are associated with fertility problems.

A possible explanation for this is, an influence of thyroid autoantibodies on the functioning of the thyroid gland. It is therefore recommended to check thyroid gland function and for the presence of autoantibodies before pregnancy. In general, 2 types of thyroid autoantibodies are known: anti-thyreoperoxidase autoantibodies and anti-thyroglobulin autoantibodies.

In case of abnormal thyroid function, treatment is sometimes necessary in regards to fertility. The risk of abnormal thyroid function is increased in women with thyroid autoantibodies during pregnancy. Therefore, thyroid function is regularly monitored during pregnancy in women with thyroid antibodies. The influence of thyroid autoantibodies on thyroid function in pregnancy after fertility treatment is not well known.

The objectives of the present study are:

1. To monitor the course of thyroid function during pregnancy and to compare between women with and without thyroid autoantibodies.

2. Compare pregnancy outcome between women with and without thyroid antibodies ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04019509
Study type Interventional
Source Universitair Ziekenhuis Brussel
Contact valerie uvin, md
Phone 486073292
Email valerieuvin@hotmail.com
Status Recruiting
Phase N/A
Start date January 1, 2019
Completion date September 1, 2022

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