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Fecal Incontinence clinical trials

View clinical trials related to Fecal Incontinence.

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NCT ID: NCT00565136 Completed - Fecal Incontinence Clinical Trials

Evaluation of Outcomes of Restoring Pelvic Floor Support With TOPAS in Women With Moderate Fecal Incontinence Symptoms

TOPAS
Start date: September 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The study purpose is to gain experience with the TOPAS system, a minimally- invasively delivered self-fixating mesh for the treatment of pelvic floor weakness in women with symptoms of moderate fecal incontinence

NCT ID: NCT00551551 Completed - Clinical trials for Urinary Incontinence

Prenatal Pelvic Floor Prevention (3PN)

Start date: November 2007
Phase: Phase 3
Study type: Interventional

Objective: Compare pelvic floor disorders (urinary incontinence, anal incontinence, genital prolapse, perineal pain, sexual troubles) 12 month after a first delivery between a group of women with prenatal pelvic floor exercises and a control group. Hypothesis: Prenatal pelvic floor exercises reduce postpartum urinary incontinence.

NCT ID: NCT00525291 Completed - Fecal Incontinence Clinical Trials

Triple Target Treatment (3T) Which Combines Stimulation With Amplitude Modulated Middle Frequency (AM-MF), Electromyography (EMG)-Triggered Stimulation and EMG-Biofeedback Compared With EMG-Biofeedback in Anal Incontinence

3T-AI
Start date: July 2007
Phase: Phase 3
Study type: Interventional

The efficacy of biofeedback and/or low frequency electrical stimulation for the treatment of anal incontinence has not been proven. First, large well-designed clinical trials are missing. Second, only few patients reach therapeutically relevant intensities with low frequency stimulation. In this study, a novel therapeutic concept, termed triple target treatment (3T) was evaluated. 3T combines stimulation with amplitude modulated middle frequency (AM-MF), electromyography (EMG)-triggered stimulation and EMG-biofeedback. 3T was compared with EMG-biofeedback alone after a nine month treatment period. Methods In this parallel-group randomised multicenter study with blinded observer we enrolled 158 patients with anal incontinence. Primary endpoints were changes from baseline to nine months in the Cleveland Clinic Score (CCS) and the St. Mark's score (Vaizey score).

NCT ID: NCT00515853 Completed - Fecal Incontinence Clinical Trials

The Role of Biofeedback in Improving Continence After Anterior Resection

Start date: November 27, 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether biofeedback exercises improve anal continence after anterior resection for rectal cancer.

NCT ID: NCT00345397 Completed - Spinal Cord Injury Clinical Trials

A Colonic Tube to Improve Bowel Function in Spinal Cord Injury

Start date: May 1, 2006
Phase: N/A
Study type: Interventional

The investigators want to know if placing a tube through the skin and into the colon to flush out the colon is safe and effective in helping spinal cord Veterans with bowel management.

NCT ID: NCT00303030 Completed - Fecal Incontinence Clinical Trials

A Randomized, Controlled, Clinical Trial of Biofeedback and Anal Injections as First Treatment of Fecal Incontinence

Start date: May 2006
Phase: Phase 1
Study type: Interventional

A short presentation of a randomized clinical trial of biofeedback and anal injections as a first treatment option of faecal incontinence. Background: Faecal incontinence affects mainly women who have suffered sphincter disruption from vaginal delivery, but individuals of all ages can be affected. The treatment of this debility is not uniform between institutions or internationally. Often is surgical reconstruction of the anal sphincter performed, or other invasive, costly treatment options. The study: We intend to conduct a randomized, controlled, clinical trial where we compare the effect of two less invasive, less costly treatment options as a first alternative: biofeedback and anal injections. Our hypothesis is that anal injections will give a better and more lasting effect than biofeedback. The primary endpoint will be change in faecal incontinence assessed by the St. Marks incontinence score. Secondary endpoints will include change in quality of life and several physiological parameters. We intend to include 62 patients in both groups, 124 all together, from 2 centres in Norway. The observation time is 2 years. We plan to include the first patient April 2006, and conclude the study by December 2010. This study can contribute to a more appropriate treatment-algorithm for these patients. Study group: - Barthold Vonen MD PhD, Department of gastroenterological surgery, University Hospital of North Norway - Rolv-Ole Lindsetmo MD PhD, Department of gastroenterological surgery, University Hospital of North Norway - Arvid Stordahl MD PhD., Department of Surgery, Østfold Hospital Fredrikstad - Ylva Sahlin MD PhD, Department of Surgery, Innlandet Hospital Hamar - Trond Dehli, MD, Department of gastroenterological surgery, University Hospital of North Norway - Kjersti Mevik, Stud. Med, University of Tromso Project manager: Trond Dehli Funding, approvals, publication: This study is funded from Northern Norway Regional Health Authority and The Institution of Norwegian Health- and rehabilitation-organizations. It has been approved by the Regional Committee for Medical Research Ethics and Norwegian Social Science Data Services. The results will be published in an international peer-reviewed journal after the Vancouver-convention's guidelines. The results will also be presented at national and international conferences. Contact: Trond Dehli, Department of gastroenterological surgery, University hospital North Norway, Breivika, 9038 Tromsø trond.dehli@unn.no tlf: +47 776 26 000

NCT ID: NCT00286520 Completed - Spinal Cord Injury Clinical Trials

Treatment of Fecal Incontinence and Constipation in Patients With Spinal Cord Injury

Start date: December 2003
Phase: Phase 4
Study type: Interventional

The study aims to compare a newly developed system for transanal colonic irrigation (Peristeen Anal Irrigation) with a bowel management regime that does not include irrigation in a prospective, randomized trial in spinal cord lesion patients (SCL- patients) with faecal incontinence and/or constipation. Population; 80 SCL- patients with faecal incontinence and/or constipation from five countries. Focus on: Bowel symptom score Neurogenic Bowel Dysfunction score Symptom related quality of life questionnaire Time expenditure for performance of bowel care ans side effects

NCT ID: NCT00230360 Completed - Constipation Clinical Trials

Diagnosis of Functional Defecation Disorders in Childhood

Start date: June 2005
Phase: N/A
Study type: Observational

Purpose To compare different kinds of diagnostic investigations in order to identify the most sensitive and least invasive when diagnosing constipation.

NCT ID: NCT00213317 Completed - Fecal Incontinence Clinical Trials

Effect of Lumbo-sacral Magnetic Stimulation on Colonic Motility

Start date: April 2005
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the effect of sacral nerve magnetic stimulation on the colonic motility in healthy subjects, in incontinent and constipated patients.

NCT ID: NCT00200057 Completed - Fecal Incontinence Clinical Trials

Sacral Nerve Stimulation Therapy for the Treatment of Chronic Fecal Incontinence

Start date: January 2002
Phase: N/A
Study type: Interventional

Fecal incontinence (FI) is a difficulty in storing gas, liquid stool or solid stool (bowel movement) in order to expel it at a proper time and place. Patients who suffer from FI may experience passive FI (difficulty in sensing stool in the rectum) or urgency (able to sense a bowel movement but cannot hold the stool until an acceptable time and place). FI is not a life-threatening disease, but it is often profoundly distressing and socially incapacitating. If a patient is suffering with symptoms of chronic FI despite trying oral medications, biofeedback and/or other more conservative treatments, a patient may be eligible to participate in a clinical research study to evaluate the safety and effectiveness of sacral nerve stimulation for the treatment of chronic fecal incontinence. One hundred-twenty (120) patients will be implanted with medical devices and followed closely for twelve months, and then once a year after that until the study closes. There are up to 20 centers in the United States.