Omega 3 Supplementation in Children With Non Alcoholic Fatty Liver

Fatty Liver Clinical Trial

— omega 3  

Official title:

the Effect of Omega 3 Fatty Acids Supplements on Antioxidant Capacity in Egyptian Children With Non Alcoholic Fatty Liver Disease

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04281121
• Other study ID #: MD 44/2017
• Status: Completed
• Phase: N/A
• Start date: March 1, 2019
• Est. completion date: February 19, 2020

Study information

• Verified date: February 2020
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

this is a prospective, interventional, open-label, randomized study on the efficacy of omega 3 fatty acids supplementation in Egyptian children with non-alcoholic fatty liver disease who had been selected from nutrition and outpatient clinic at Pediatric hospital, Ain Shams University

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: February 19, 2020
• Est. primary completion date: January 25, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 6 Years to 16 Years

Eligibility

Inclusion Criteria:

Children between 5 - 16 years old with diffusely hyper echogenic liver at ultrasonography were included in the study.

Exclusion Criteria:

• Patients with secondary causes of steatosis including total parenteral nutrition, drugs causing fatty liver disease for example steroids, hepatitis A, B, C, cytomegalovirus, Epstein-Barr virus infections, autoimmune liver disease, metabolic liver diseases, Wilson's disease, and alpha-1-antitrypsin deficiency.

• Patients currently taking fish oil supplements.

• Patients with systemic illness such as cardiac and kidney diseases.

Related Conditions & MeSH terms

• Fatty Liver
• Non-alcoholic Fatty Liver Disease

Intervention

Dietary Supplement:
• omega 3 fatty acids
: Life style modification, diet regimen and Omega-3 fatty acids supplementation: The dose of omega-3 fatty acids depended on the weight of patients according to World Health Organization recommendations 400 milligrams per 10 kilograms of body weight and had been given into two doses per day, before morning and evening meals

Locations

Country	Name	City	State
Egypt	Pediatrics hospital Ain shams University	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	grade of fatty liver in children	improvement	3 month