Effects of a Time Restricted Eating Protocol on Cyclists (TRECYC)

Fasting and Performance Clinical Trial

— TRECYC  

Official title:

Effects of 4 Weeks of Time Restricted Eating Protocol on Performance, Metabolism and Blood Outcomes in Elite Cyclists

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04320784
• Other study ID #: AP1019
• Status: Completed
• Phase: N/A
• Start date: January 6, 2018
• Est. completion date: May 15, 2018

Study information

• Verified date: March 2020
• Source: University of Padova
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

We sought to investigate the effects of 4 weeks of 16/8 time restricted eating (TRE) with windows of 16 hours of fasting and 8 hours of eating) on elite cyclists' performance, metabolic and blood parameters.

Description:

Sixteen elite under-23 cyclists were randomly assigned to a TRE group or to a control group (CTRL) with a traditional meal pattern. The TRE group consumed 100% of its estimated daily energy needs in an 8-hour time window: from 10:00 AM (ante meridiem) to 6:00 PM (post meridiem) whilst the CTRL group consumed 100% of its estimated daily energy needs in 3 meals between 7:00 AM and 9:00 PM. During the experimental period, training loads were similar in the two groups. Athletes were tested before and after 4 weeks of the intervention. Body composition , basal metabolism, performances indexes and blood parameters were measured.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: May 15, 2018
• Est. primary completion date: March 30, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 24 Years

Eligibility

Inclusion Criteria:

• elite under 23 cyclists male

Exclusion Criteria:

• adherence to special diets

• use of nutritional supplements (except a daily multivitamin-mineral and/or protein supplement)

• use of medications

Related Conditions & MeSH terms

• Fasting and Performance

Intervention

Other:
• Time restricted eating
TRE group consumed 100% of its estimated daily energy needs in an 8-hour time window: from 10:00 AM to 6:00 PM
• Control
CTRL group consumed 100% of its estimated daily energy needs in 3 meals between 7:00 AM and 9:00 PM

Locations

Country	Name	City	State
Italy	Nutrition and Exercise Lab, DSB, University of Padova	Padova

Sponsors (3)

Lead Sponsor	Collaborator
University of Padova	University of Palermo, University of Pavia

Country where clinical trial is conducted

Italy, 

References & Publications (4)

Moro T, Tinsley G, Bianco A, Marcolin G, Pacelli QF, Battaglia G, Palma A, Gentil P, Neri M, Paoli A. Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk f — View Citation

Paoli A, Tinsley G, Bianco A, Moro T. The Influence of Meal Frequency and Timing on Health in Humans: The Role of Fasting. Nutrients. 2019 Mar 28;11(4). pii: E719. doi: 10.3390/nu11040719. Review. — View Citation

Tinsley GM, Forsse JS, Butler NK, Paoli A, Bane AA, La Bounty PM, Morgan GB, Grandjean PW. Time-restricted feeding in young men performing resistance training: A randomized controlled trial. Eur J Sport Sci. 2017 Mar;17(2):200-207. doi: 10.1080/17461391.2 — View Citation

Tinsley GM, Moore ML, Graybeal AJ, Paoli A, Kim Y, Gonzales JU, Harry JR, VanDusseldorp TA, Kennedy DN, Cruz MR. Time-restricted feeding plus resistance training in active females: a randomized trial. Am J Clin Nutr. 2019 Sep 1;110(3):628-640. doi: 10.109 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	VO2max	Maximal oxygen consumption (in ml O2/Kg/min) measured during a cycloergometer incremental test through a gas analyses	4 weeks
Primary	fat mass	fat mass measured through body impedence analyser	4 weeks
Primary	lean body mass	lean body mass mass measured through body impedence analyser	4 weeks
Secondary	white blood cells	white blood cells as thousands per microliter	4 weeks
Secondary	Eosinophils	Eosinophils as percentage of total white blood cells	4 weeks
Secondary	Monocytes	Monocytes as percentage of total white blood cells	4 weeks
Secondary	Basophiles	Basophiles s percentage of total white blood cells	4 weeks
Secondary	Hematocrit	Hematocrit as percentage	4 weeks
Secondary	Haemoglobin	Haemoglobin as gram per Liter	4 weeks
Secondary	Mean cell volume	mean cell volume as femtonLiter	4 weeks
Secondary	mean cell haemoglobin	mean cell haemoglobin as picograms	4 weeks
Secondary	ESR (Erythrocyte sedimentation rate )	ESR as millimeters per hour	4 weeks
Secondary	CRP (C-reactive protein)	CRP as milligram per deciliter	4 weeks
Secondary	Total cholesterol	Total cholesterol as milligram per deciliter	4 weeks
Secondary	TG (triglycerides)	TG as milligram per deciliter	4 weeks
Secondary	glucose	glucose as milligram per deciliter	4 weeks
Secondary	creatinine	creatinine as milligram per deciliter	4 weeks
Secondary	creatin kinase	creatin kinase as milligram per deciliter	4 weeks
Secondary	iron	iron as microgram per deciliter	4 weeks
Secondary	ferritin	ferritin as microgram per liter	4 weeks
Secondary	transferrin	ferritin as milligram per deciliter	4 weeks
Secondary	TSH (Thyroid Stimulating Hormone)	TSH as micro international unit per milliliter	4 weeks
Secondary	T3 (triiodothyronine) free	T3 free as picogram per milliliter	4 weeks
Secondary	Testosterone free	Testosterone free as picogram per milliliter	4 weeks
Secondary	IL-6	IL-6 as picogram per milliliter	4 weeks
Secondary	TNFalfa	TNFalfa as picogram per milliliter	4 weeks
Secondary	IGF-1	IGF-1 as nanogram per milliliter	4 weeks
Secondary	Insulin	Insulin micro international unit per milliliter	4 weeks