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Eye Diseases clinical trials

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NCT ID: NCT06119386 Completed - Dry Eye Clinical Trials

Quantum Molecular Resonance Electrotherapy in Severe Dry Eye Disease

QMR
Start date: November 3, 2022
Phase: N/A
Study type: Interventional

To evaluate the efficacy and safety of Quantum Molecular Resonance (QMR) treatment in patients with severe dry eye disease (DED), as well as its effects on aqueous-deficient (ADDE), evaporative (EDE) and mixed (MDE) dry eye.

NCT ID: NCT06058559 Completed - Dry Eye Disease Clinical Trials

Effect of Sunflower Lecithin Supplementation on Meibomian Gland Function in Adults With Dry Eye Disease

Start date: June 20, 2023
Phase: N/A
Study type: Interventional

This prospective study will evaluate the effect of oral sunflower lecithin dietary supplementation on meibomian gland function in adults with dry eye disease.

NCT ID: NCT06018571 Completed - Dry Eye Disease Clinical Trials

Burden of Illness and Treatment Assessment of Patients With Dry Eye Disease: A Cross-Sectional Survey of Real-World Patients With Dry Eye Disease in the US

Start date: June 2, 2022
Phase:
Study type: Observational

This study employed secondary database analysis of the Adelphi Dry Eye Disease (DED) Disease Specific Programme™ (DSP™), a templatized cross-sectional survey with retrospective data collection that is administered by Adelphi to a convenience sample of patients diagnosed with DED, and their consulting physicians in the United States. In addition to the survey data, the DED DSP also included recorded medical history data as reported by physicians (optometrists, ophthalmologists or refractive surgeons).

NCT ID: NCT05968443 Completed - Eye Diseases Clinical Trials

Dafilon® Suture Material in Patients Undergoing Ophthalmic Surgery

OPHTHADA
Start date: January 8, 2019
Phase:
Study type: Observational

This is an observational, retrospective postmarket clinical follow-up study and includes all patients who underwent any ophthalmic surgery using Dafilon® suture in the selected centres between 2018 and 2020, therefore no sample size can be given but the planned sample size shall be at least 200 eyes (around 100 patients depending on the number of operated eyes per patient) to conduct meaningful subgroup analysis.

NCT ID: NCT05936489 Completed - Presbyopia Clinical Trials

Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Presbyopia

Start date: July 6, 2023
Phase: Phase 1
Study type: Interventional

This is a single-center, open-label, randomized study to assess the plasma pharmacokinetic profile of LNZ101 and LNZ100.

NCT ID: NCT05930444 Completed - Eye Diseases Clinical Trials

Multimodal Machine Learning for Auxiliary Diagnosis of Eye Diseases

Start date: July 21, 2023
Phase:
Study type: Observational

With rapid advancements in natural language processing and image processing, there is a growing potential for intelligent diagnosis utilizing chatGPT trained through high-quality ophthalmic consultation. Furthermore, by incorporating patient selfies, eye examination photos, and other image analysis techniques, the diagnostic capabilities can be further enhanced. The multi-center study aims to develop an auxiliary diagnostic program for eye diseases using multimodal machine learning techniques and evaluate its diagnostic efficacy in real-world outpatient clinics.

NCT ID: NCT05888519 Completed - Dry Eye Disease Clinical Trials

Evaluation of Safety and Tolerability of Investigational Ocular Lubricants

Start date: July 24, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate investigational ocular lubricants for their safety and tolerability on subjects with mild to moderate dry eye disease.

NCT ID: NCT05857579 Completed - Dry Eye Disease Clinical Trials

Diamond Bur Microblepharoexfoliation, Intense Pulse Light and Meibomian Gland Expression for Evaporative Dry Eye

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess the efficacy and safety of microblepharoeexfoliation (MBE), intense pulse light (IPL) and meibomian gland expression (MGX) combination in patients with meibomian gland dysfunction (MGD). The main question it aims to answer are: - Does MBE-IPL-MGX treatment improve dry eye symptoms? - Does MBE-IPL-MGX treatment improve dry eye signs? Participants were assigned to receive either three sessions of MBE-IPL-MGX treatment and home-based therapy (treatment group) or home-based therapy alone (control group). The investigators will compare both groups to see if MBE-IPL-MGX treatment is superior to home-based therapy.

NCT ID: NCT05853315 Completed - Clinical trials for Basal Cell Carcinoma

BCC Excision Revisited

Start date: November 12, 2019
Phase:
Study type: Observational

To readdress basal cell carcinoma (BCC) in the periocular region to prove histologically controlled surgical treatment efficacy and to identify high-risk characteristics.

NCT ID: NCT05841043 Completed - Dry Eye Disease Clinical Trials

Efficacy and Safety of SHR8028 Eye Drops for the Treatment of Dry Eye Disease

Start date: March 4, 2021
Phase: Phase 3
Study type: Interventional

The study is being conducted to assess the efficacy, safety and tolerability of SHR8028 eye drops in comparison to the vehicle for the treatment of dry eye disease.