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Extraesophageal Reflux clinical trials

View clinical trials related to Extraesophageal Reflux.

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NCT ID: NCT04581174 Completed - Clinical trials for Extraesophageal Reflux

Effect of Extraesophageal Reflux on Inferior Nasal Turbinates Hypertrophy

Start date: October 15, 2020
Phase: N/A
Study type: Interventional

The study examines the severity of extraesophageal reflux using oropharyngeal pH monitoring in patients with varying degrees of lower turbinates hypertrophy.

NCT ID: NCT03904758 Completed - Clinical trials for Extraesophageal Reflux

Extraesophageal Reflux - Feasibility of Measurement of Pepsin in Saliva as a Diagnostic Option

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

The diagnostics of extraesophageal reflux (EER) is challenging. Currently, 24-h dual-probe esophageal pH monitoring or impedance is considered the best diagnostic method for EER. The 24-h oropharyngeal pH monitoring is a newer method aimed at detecting episodes of reflux to the oropharynx. Unfortunately, all these methods have many disadvantages. Pepsin detection in saliva would be an almost ideal diagnostic technique. However, data of its reliability is lacking. The aim of the study is to compare results of oropharyngeal pH monitoring and esophageal impedance monitoring, compared to a quantified pepsin presence in the saliva obtained immediately prior to 24-hour monitoring and to evaluate the feasibility of this technique as a routine option of diagnosing the presence of extraesophageal reflux.

NCT ID: NCT01755221 Completed - Clinical trials for Extraesophageal Reflux

Positive Predictive Value of the Dx-pH Probe for Predicting PPI Response in LPR

Start date: August 2012
Phase:
Study type: Observational

The purpose of this research study is to better understand whether information obtained from a pH probe can help physicians predict whether a patient will respond to the medication that is prescribed for laryngopharyngeal reflux (LPR). The current treatment given to individuals who are diagnosed with LPR is a course of proton pump inhibitor (PPI) medication. Subjects who agree to participate in this study will have a small flexible tube (about the width of a piece of cooked spaghetti) placed in their throat. This tube measures the pH in the throat over a period of 24 hours and helps physicians study the relationship between pH level, LPR symptoms, and the effectiveness of PPI therapy. This study may help physicians find out if certain symptoms or characteristics can help them predict if the PPI medication will be effective for each patient. After probe removal, subjects will receive compensation. They will return to the clinic at their regularly scheduled follow-up visit with the physician, 8 to 12 weeks after starting the PPI medication. At that time, subjects can choose to participate in an optional probe placement.