Glucose and Fructose Stimulated Brain Activity in Obese Subjects Before and After Bariatric Surgery

Exploratory Behavior Clinical Trial

Official title:
Glucose and Fructose Stimulated Brain Activity in Obese Subjects Before and After Bariatric Surgery

Status Completed

Clinical Trial Summary

The objective is to investigate neuro-anatomical correlates of the regulation of energy intake by means of functional MRI before and after bariatric surgery. Administration of glucose as well as fructose is followed by functional brain MRI, and findings are correlated with serum glucagon-like peptide 1 (GLP-1) levels as an endogenous satiety signal in obese humans.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Exploratory Behavior

Clinical Trial Details

NCT number	NCT02902224
Study type	Interventional
Source	University Hospital, Basel, Switzerland
Contact
Status	Completed
Phase	N/A
Start date	April 2014
Completion date	August 2016

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02589613` - Glucose and Fructose Stimulated Brain Activity in Obese Subjects	N/A
Completed	`NCT02255812` - Taste Physiology in Healthy, Normal-weight Volunteers	N/A
Completed	`NCT01918566` - The Role of Endogenous GLP-1 (Glycolipoprotein) in Regulating Glucose Stimulated Brain Activity	N/A
Completed	`NCT01875913` - The Power of Curiosity: Leveraging Curiosity to Motivate People to Complete Health Risk Assessments	N/A
Recruiting	`NCT03604614` - Hyperthermic Intraperitoneal Chemotherapy for Advanced Gastric Cancer With Peritoneal Metastatis	Phase 2
Completed	`NCT01615289` - Neural Effects of Green Tea Extract on Dorsolateral Prefrontal Cortex	N/A