Acute Effects of Three Different Types Single Leg Exercise in Copd

Exercise Clinical Trial

— COPD  

Official title:

Acute Effects of Three Different Types Single Leg Exercise in Copd

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06466213
• Other study ID #: GO23-193
• Status: Recruiting
• Phase: N/A
• Start date: February 20, 2024
• Est. completion date: January 2, 2025

Study information

• Verified date: June 2024
• Source: Hacettepe University
• Contact: elif kocaaga, Ms
• Phone: +903123052525
• Email: elifkocaaga86[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

COPD presents not only respiratory symtoms but also vascular or muscle dysfunction. Exercise training is important for aerobic performance increasing. Generally results show exercise training with both lower limb. Increaed arterial stiffness and muscle oxygenation are observed in COPD. One leg exercise result is not enough to highlight these parameters.

Description:

Acute Effects of Three Different Types Single Leg Exercise in Copd

single bout high intensity interval training

single bout continuous exercise training single bout resistance training

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 45
• Est. completion date: January 2, 2025
• Est. primary completion date: January 2, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years and older

Eligibility

Inclusion Criteria:

• COPD patients that applied to physiotherapy

• cooperate to test

• no severe ortopedical and neurological disease no severe cardiovascular disease volunteer to study

Exclusion Criteria:

• have an acute exacerbation

• hypoxemia [PaO2] <55 mmHg

• no cooperated to test no volunteer to study having ortophedical and neurological diesase that affecting of tests having severe cardiovascular disease

Related Conditions & MeSH terms

• Exercise

Intervention

Other:
• single exercise bout about one-leg exercise
cycle exercise includes single leg

Locations

Country	Name	City	State
Turkey	Elif Kocaaga	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Hacettepe University

Country where clinical trial is conducted

Turkey, 

References & Publications (1)

Evans RA, Dolmage TE, Mangovski-Alzamora S, Romano J, O'Brien L, Brooks D, Goldstein RS. One-Legged Cycle Training for Chronic Obstructive Pulmonary Disease. A Pragmatic Study of Implementation to Pulmonary Rehabilitation. Ann Am Thorac Soc. 2015 Oct;12(10):1490-7. doi: 10.1513/AnnalsATS.201504-231OC. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	six minute walk test	six minute walk test in meter	beginning, day 1
Secondary	cardiopulmonary exercise test	VO2 max will be recorded as ml/kg/min will be recorded from incremental cycle cpet test	beginning, day 2
Secondary	single leg extremity test	VO2 max will be recorded as ml/kg/min will be recorded from incremental cycle cpet test	beginning, day 3
Secondary	lung function	FVC in % , FEV1 in %, FEV1/FVC ratio, PEF in % and FEF 25-75 in %	beginning, day 1
Secondary	muscle strength (isometric)	quadriceps isometric muscle strength will be recorded as kilogram	beginning day 1
Secondary	muscle strength (10 repeated max)	quadriceps 10 repeated max muscle strength will be recorded as kilogram	beginning, day 1
Secondary	continous exercise acute (single leg)	VO2 max will be recorded as ml/kg/min will be performed from incremental cycle exercise at single session	beginning day 4
Secondary	high intensity interval training acute exercise (single leg)	VO2 max will be recorded as ml/kg/min will be performed from incremental cycle exercise at single session	beginning day 5
Secondary	strength training acute exercise (single leg)	VO2 max will be recorded as ml/kg/min will be performed from incremental cycle exercise at single session	beginning day 4,5,6
Secondary	muscle oxygenation	minumum muscle oxygenation level will be presented as percentage	beginning day 4,5,6
Secondary	arterial stifness	Aix@75 in %	beginning day 2,3, 4,5,6