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Ketone Administration During Inactivity and Retraining

Exercise Clinical Trial

Official title:
Effect of Oral Ketone Administration During Inactivity-induced Muscle Atrophy and Retraining-induced Regeneration

Clinical Trial Summary

The aim of this study is to investigate the effect of oral ketone administration during inactivity-induced muscle atrophy and retraining-induced regeneration. Potential changes in muscle function (cycling performance, knee-extension force and power, jump height) and mass, blood flow and the muscular extracellular matrix will be the main focus. In this context, the dominant leg of the participants (n=24) will be immobilized with a brace for 2 weeks and subsequently retrained in a 4-week progressive resistance exercise training program to stimulate muscle regeneration. During the immobilization and rehabilitation period, participants receive either ketone ester (KE) or placebo (CON). 4 experimental sessions are performed during this time frame in order to evaluate the effects of the trial.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05398042
Study type Interventional
Source KU Leuven
Contact Peter Hespel, Prof.
Phone +3216329091
Email peter.hespel@kuleuven.be
Status Recruiting
Phase Phase 2
Start date December 15, 2021
Completion date August 31, 2022
View Details
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