Effect of One Minute of Resistance Exercise Per Day on Muscular Strength (The ONE Study)

Exercise Clinical Trial

Official title:

The ONE Study: Effect of One Minute of Resistance Exercise Per Day on Muscular Strength

Clinical Trial Details — Status: Suspended

Administrative data

• NCT number: NCT03981250
• Other study ID #: 200180137
• Status: Suspended
• Phase: N/A
• Start date: June 20, 2019
• Est. completion date: December 31, 2021

Study information

• Verified date: September 2020
• Source: University of Glasgow
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study will evaluate the effect of one minute of resistance exercise per day on muscular strength in adults. Half of the participants will undergo a 12-week home-based resistance exercise programme, while the other half will continue their usual lifestyle behaviour.

Description:

A resistance training programme can lead to a variety of health benefits including increases in muscle size and strength. Other potential health benefits of resistance training include reduction of body fat, increased metabolic rate, improve insulin sensitivity, blood glucose tolerance and blood lipid profiles. Meta-analyses indicate that while performing resistance exercise two or more times per week of resistance exercise per muscle group appears to be optimal to maximise strength gains, a single set of resistance exercise per muscle group per week, if performed to failure is sufficient to induce substantial strength changes.

The current physical activity guidelines recommend undertaking muscle strengthening activities involving major muscle groups two days a week or more, as well as undertaking at least 150 minutes per week of moderate intensity physical activity (or 75 minutes per week of vigorous intensity physical activity). However, only small portion of the population achieves the muscle strengthening aspect of the guidelines. As lack of time is often cited as a reason not to engage in physical activity, this study is seeking to investigate a low time-commitment approach to resistance exercise which could increase muscular strength. To address this, the present study will to split a typical single session of resistance exercise involving several exercises across different muscle groups into separate 1-minute micro-sessions where a different muscle group is exercised on each day of the week. The aim is to determine the effects of a one-minute-per-day home-based resistance exercise training on muscular strength.

The study is a randomized control trial in which the control group will continue their lifestyle behaviour and will be asked not to increase their physical activity levels and the exercise group will perform a 12-week home-based resistance exercise programme, involving doing one minute of resistance exercise per day on six days of the week, with a different exercise performed on each day. All participants will be measured at baseline, 4 weeks, 8 weeks and 12 weeks.

Recruitment information / eligibility

• Status: Suspended
• Enrollment: 56
• Est. completion date: December 31, 2021
• Est. primary completion date: October 28, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Aged 18-65 years

Exclusion Criteria:

• Diabetes

• Uncontrolled hypertension (blood pressure > 150/90 on medication).

• History of cardiovascular disease

• Undertaking more than 150 minutes of moderate intensity or 75 minutes of vigorous physical activity or undertaking any resistance exercise.

• Other significant illness that would prevent the participant to undertake physical activity.

Related Conditions & MeSH terms

• Exercise

Intervention

Behavioral:
• 12-week home-based resistance exercise programme
Participants will perform 6 exercises (press-ups, squats, squat jumps, plank, upright row and seated row) for one minute, aiming for the maximum number of repetitions. Participants will perform one exercise per day, for 6 days a week, for 12 weeks.

Locations

Country	Name	City	State
United Kingdom	University of Glasgow	Glasgow

Sponsors (1)

Lead Sponsor	Collaborator
University of Glasgow

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle strength	Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).	Change between baseline and 4 weeks
Primary	Muscle strength	Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).	Change between baseline and 8 weeks
Primary	Muscle strength	Change in 1-RM (one repetition maximum) (kg) for bench press, leg press and lat pull down (kg).	Change between baseline and 12 weeks
Secondary	Muscle endurance	Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.	Change between baseline and 4 weeks
Secondary	Muscle endurance	Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.	Change between baseline and 8 weeks
Secondary	Muscle endurance	Change in maximal number of repetitions with a load of 50% of baseline 1-RM for bench press, leg press and lateral pull down.	Change between baseline and 12 weeks
Secondary	Weight	Change in weight (kg).	Change between baseline and 4 weeks
Secondary	Weight	Change in weight (kg).	Change between baseline and 8 weeks
Secondary	Weight	Change in weight (kg).	Change between baseline and 12 weeks
Secondary	Waist	Change in waist circumference (cm).	Change between baseline and 4 weeks
Secondary	Waist	Change in waist circumference (cm).	Change between baseline and 8 weeks
Secondary	Waist	Change in waist circumference (cm).	Change between baseline and 12 weeks
Secondary	Body composition	Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).	Change between baseline and 4 weeks
Secondary	Body composition	Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).	Change between baseline and 8 weeks
Secondary	Body composition	Change in fat mass and free fat mass measured by Bioelectrical Impedance Analysis (BIA).	Change between baseline and 12 weeks
Secondary	Muscle thickness	Change in muscle thickness of vastus lateralis (mm) measured with ultrasound.	Change between baseline and 12 weeks
Secondary	Grip strength	Change in grip strength (kg) measured using a hand grip dynamometer	Change between baseline and 4 weeks
Secondary	Grip strength	Change in grip strength (kg) measured using a hand grip dynamometer	Change between baseline and 8 weeks
Secondary	Grip strength	Change in grip strength (kg) measured using a hand grip dynamometer	Change between baseline and 12 weeks