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Exanthema clinical trials

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NCT ID: NCT06403371 Active, not recruiting - White Spot Lesion Clinical Trials

The Effect of Fluoride Varnish on White Spot Lesion in Clear Aligner Orthodontic Patients

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Fluoride varnish is being applied on the teeth surfaces of patients undergoing orthodontic treatment just before receiving their clear aligners. The effect of the varnish was investigated if it can reduce the incidence of enamel demineralization or not.

NCT ID: NCT05738369 Active, not recruiting - White Spot Lesion Clinical Trials

The Effect of Probiotic Lozenges on White Spot Lesion Development in Orthodontic Patients

Start date: February 14, 2022
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial was to investigate the effect of probiotic lozenges on the development of white spot lesions (WSLs) compared to a positive control, and no treatment.

NCT ID: NCT05120362 Active, not recruiting - Acneiform Eruptions Clinical Trials

A Study to Evaluate JAK Inhibitor Cream in EGFR-inhibitor-induced Skin Rash

Start date: November 3, 2021
Phase: N/A
Study type: Interventional

Epidermal growth factor receptor inhibitors (EGFRIs) are widely used targeted agents that have been approved for the treatment of various tumor types. In some clinical studies with EGFRIs, the incidence of dermatology AE, the skin rash, is reportedly as high as 95%, which profoundly impact the patients' quality of life. However no treament for onset skin rash has been approved to be effective by any clinical trial yet. Janus kinase (JAK) inhibitor, has been approved for or studied in a variety of skin conditions such as alopecia areata, atopic dermatitis, and psoriasis. Thus the investigators intend to evaluate the efficacy and safety of JAK inhibitor cream for the treatment of EGFRIs-induced skin rash in cancer patients.

NCT ID: NCT02675036 Active, not recruiting - Clinical trials for Tooth Eruption,Ectopic

Interceptive Study of Ectopic Eruption of Permanent Maxillary Canine Teeth

Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to see whether extraction of the primary canine tooth or extraction of both the primary canine - and the primary first molar tooth is most effective in the treatment of palatally ectopic canine teeth in the maxilla. In addition the study will also measure pain and discomfort in relation to these two treatment alternatives.

NCT ID: NCT01315990 Active, not recruiting - Clinical trials for Colorectal Cancer Metastatic

FOLFIRI in Combination With Cetuximab in the First-line Treatment of Metastatic Colorectal Cancer Including a Regular Dermal Prophylaxis to Prevent Acneiforme Follicular Exanthema

DERMATUX
Start date: January 2011
Phase: Phase 4
Study type: Interventional

The purpose of this interventional study is to assess the progression free survival (one year) of patients with treatment of FOLFIRI and cetuximab, combined with an optional dermal prophylaxis. Further Objectives: 1. Development of acneiforme follicular exanthema >= grade 2 2. Duration until development of acneiforme follicular exanthema >= grade 2 3. Development of paronychia 4. Development skin fissure (hand and foot) 5. Objective remission according RECIST 1.1 6. Rate of secondary resections of liver metastasis with a curative approach 7. Assessment of safety and tolerability 8. Overall survival 9. Progression free survival