Deep Brain Stimulation Effects in Essential Tremor

Status Recruiting

Clinical Trial Summary

Deep Brain Stimulation (DBS) is an effective therapy for patients with medically refractory essential tremor. However, DBS programming is not standardized and multiple clinic visits are frequently required to adequately control symptoms. The investigators aim to longitudinally record brain signals from patients using a novel neurostimulator that can record brain signals. The investigators will correlate brain signals to clinical severity scores to identify pathological rhythms in the absence of DBS, and we will study the effects of DBS on these signals in order to guide clinical programming.

Clinical Trial Description

The development of newer technologies has allowed clinicians and researchers to better understand pathophysiological underpinnings of different disorders managed with neuromodulation. The is now the ability to stream brain signals from a newly FDA approved device, the Medtronic Percept. The investigators will study the longitudinal effects of DBS on the brain signals that are found to correlate with tremor severity as measured with wireless wearable sensors. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04581941
Study type	Observational
Source	University of Florida
Contact	Aysegul Gunduz, PhD
Phone	3522736877
Email	agunduz@ufl.edu
Status	Recruiting
Phase
Start date	December 5, 2020
Completion date	December 30, 2025

View Details

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