Effect of Vitamin K 2 on Vascular Calcification in Hemodialysis Patients

Status Recruiting

Clinical Trial Summary

The aim of this study is to assess the effect of supplementation of vitamin K2 (menaquinone, MK-7) and cholecalciferol (inactive vitamin D) on circulating levels of calcification regulators and to assess their safety in pediatric patients on regular hemodialysis patients.

Clinical Trial Description

Vascular calcification occurs in more than half of chronic renal failure patients, which mainly appears in the large and medium size arteries [3, 4]. It seems that vas¬cular calcification is caused by dynamic imbal-ance of intravascular calcium and phosphorus. However, more and more studies pointed out that vascular calcification were related with local cell's function and biological characteris¬tics.

The aim of this study is to assess the effect of supplementation of vitamin K2 (menaquinone, MK-7) and cholecalciferol (inactive vitamin D) on circulating levels of calcification regulators and to assess their safety in pediatric patients on regular hemodialysis patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04145492
Study type	Interventional
Source	Ain Shams University
Contact
Status	Recruiting
Phase	Phase 2/Phase 3
Start date	September 1, 2019
Completion date	February 1, 2020

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