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Effects of Empagliflozin on Endogenous Glucose Production in End Stage Renal Disease(ESRD).

End Stage Renal Disease Clinical Trial

Official title:
A Phase II,Randomized,Cross-over,Double-blind, Placebo- Controlled,Single Center Study of the Effect of Empagliflozin a SGLT-2 Inhibitor,on Endogenous Glucose Production and Plasma Glucagon Levels in Patients With ESRD

Clinical Trial Summary

A study of the effects of empagliflozin, a SGLT-2 inhibitor, on endogenous glucose production and plasma glucagon levels in patients with end-stage renal disease (ESRD)

Clinical Trial Description

The impact of SGLT-2 inhibition on endogenous glucose production and plasma glucagon levels will be compared measured in patients with ESRD.The secondary endpoints are the mean difference in plasma glucose, insulin, c-peptide, FFA,GH, epinephrine, norepinephrine, cortisol and blood pressure during the last hour of the experiment between empagliflozin versus placebo administration in patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03713190
Study type Interventional
Source University of Pisa
Contact
Status Completed
Phase Phase 2
Start date September 10, 2018
Completion date March 15, 2020
View Details
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