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NCT03237130 Clinical Trial

Prediction of Lymphatic Metastasis in Esophageal Cancer by CT Radiomics

Esophagus Cancer Clinical Trial

Official title:
Prediction of Lymphatic Metastasis in Esophageal Cancer by CT Radiomics

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03237130
Other study ID # CTRadiomics-LMesophagus-BNSF
Secondary ID
Status Completed
Phase
First received
Last updated
Start date February 15, 2017
Est. completion date May 15, 2020

Study information
Verified date January 2021
Source Beijing Cancer Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study proposes to establish a CT radiomics-based prediction model for identifying metastasis lymph nodes in esophageal cancer.

Description:

This study proposes to establish an image feature extraction and selection method for identifying lymph node metastasis of esophageal cancer.The study will consider the relationship between the main lesion and the suspected lymph node, extract association characteristics in order to improve the sensitivity and specificity of the CT radiomics-based prediction model for identifying metastasis lymph nodes. The study includes the construction of CT radiomics-based prediction model and the validation of the prediction model.

Recruitment information / eligibility
Status Completed
Enrollment 133
Est. completion date May 15, 2020
Est. primary completion date November 7, 2019
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - pathologically proven esophageal cancer - scheduled to preoperative enhanced chest CT and undergo surgery - sign the patient informed consent Exclusion Criteria: - failed to receive preoperative enhanced chest CT or undergo surgery - inavailable pathological results for local lymph node status - inquality of CT images for feature extraction - patient quit

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• preoperative enhanced chest CT examination
Each patient will receive preoperative enhanced chest CT examination, and their CT images will be used for analysis

Locations
Country Name City State
China Beijing Cancer Hospital Beijing Beijing

Sponsors (1)
Lead Sponsor Collaborator
Beijing Cancer Hospital

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary pathological local lymph node status pathological lymph node status is defined as lymph node metastasis exist or not Pathologic evaluation will be performed for each patient within 1 week after surgery
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