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Transient Receptor Potential Vanilloid One (TRPV1) Receptor Expression in Children With Retrosternal Pain — TRPV1  

Esophagitis Clinical Trial

Official title:
Capsaicin-sensitive Transient Receptor Potential Vanilloid One (TRPV1) and Tyrosine Kinase (TrkA) Receptor Expression in Children With Retrosternal Pain

Clinical Trial Summary

We would like to evaluate the changes in nerve innervation and TRPV1 receptor expression along with microscopic changes associated with heart burn and abdominal pain

Clinical Trial Description

Approximately 5% of children between 10-17 years of age report symptoms of heart burn, epigastric pain or regurgitation. This study will evaluate the changes in nerve innervation and TRPV1 receptor expression in children having upper endoscopy for evaluation of heart burn and abdominal pain. ;

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00677378
Study type Observational
Source Medical College of Wisconsin
Contact
Status Completed
Phase N/A
Start date December 2006
Completion date October 2015
View Details
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