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Study of Nimotuzumab to Treat Esophageal Squamous Cell Carcinoma.

Esophageal Squamous Cell Cancer Clinical Trial

Official title:
Phase IIa Study of Nimotuzumab in Second or Late- Line Treatment of Patients With Locally Advanced or Metastatic Esophageal Squamous Cell Carcinomas

Clinical Trial Summary

Nimotuzumab is an IgG1 humanized monoclonal antibody that recognized an epitope located in the extra cellular domain of the human epidermal growth factor receptor (EGFR). Clinical efficacy has been shown in adult with head and neck cancer. The study assessed the safety and efficacy of different dosage of Nimotuzumab in second or late- line treatment of patients with locally advanced or metastatic esophageal squamous cell carcinomas.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01993784
Study type Interventional
Source Peking University
Contact Zhihao Lu, MD
Phone 86-10-88196561
Email pppeirain@126.com
Status Recruiting
Phase Phase 1/Phase 2
Start date August 2013
Completion date June 2014
View Details
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