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NCT05303740 Clinical Trial

Anlotinib Retrospective Study for Esophageal Cancer

Esophageal Neoplasms Clinical Trial

Official title:
Efficacy and Safety of Anlotinib in the First-line or Second-line Treatment of Locally Advanced or Metastatic Esophageal Cancer in China, a Retrospective, Multicenter, Real-world Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05303740
Other study ID # L2021-Y348-001
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2019
Est. completion date March 1, 2022

Study information
Verified date March 2022
Source The First Affiliated Hospital of Zhengzhou University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The efficacy of anlotinib in the treatment of esophageal cancer has been confirmed. The purpose of this study was to retrospectively observe the efficacy and safety of anlotinib in the first and second line of advanced esophageal cancer in the real world.

Recruitment information / eligibility
Status Completed
Enrollment 300
Est. completion date March 1, 2022
Est. primary completion date March 1, 2022
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - Esophageal cancer diagnosed pathologically or clinically - Patients who use anlotinib alone, or combined with chemoradiotherapy, or plus PD-1 inhibitors in first-line or second-line treatment Exclusion Criteria: None

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Anlotinib
This is an observational study.

Locations
Country Name City State
China The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan

Sponsors (1)
Lead Sponsor Collaborator
Feng Wang

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary PFS Progression Free Survival From date of admission until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 24 months
Secondary OS Overall Survival From date of admission until the date of death from any cause, assessed up to 24 months
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