Changes in Esophageal Motility and Swallowing Symptoms After Thyroid Surgery

Esophageal Motility Disorders Clinical Trial

Official title:

Changes in Esophageal Motility and Swallowing Symptoms After Thyroid Surgery - a Prospective Cohort Study

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03100357
• Other study ID #: SOLOIST4
• Status: Active, not recruiting
• Phase: N/A
• First received: March 14, 2017
• Last updated: March 28, 2017
• Start date: October 31, 2014
• Est. completion date: September 30, 2018

Study information

• Verified date: March 2017
• Source: University of Southern Denmark
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The pronounced effect of goiter on the esophagus needs further exploration, as the mechanisms by which goiter leads to swallowing difficulties are unknown. By investigating esophageal motility using high resolution esophageal manometry before and after thyroidectomy we seek to examine the impact of the goiter mass on the esophagus and swallowing with six months follow-up.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 39
• Est. completion date: September 30, 2018
• Est. primary completion date: March 2, 2017
• Gender: All
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

• Patients with symptomatic benign nodular goiter referred for thyroidectomy

Exclusion Criteria:

• Previous surgery to the neck;

• Suspicion of thyroid cancer

• Age below 20 years or above 80 years

• Neuromuscular disease.

Related Conditions & MeSH terms

• Esophageal Motility Disorders
• Esophageal Spasm, Diffuse

Intervention

Other:
• Thyroidectomy
Thyroid surgery for benign nodular goiter

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Southern Denmark

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Motility disturbances	Change in number of failed swallowings from baseline	Before and six months following thyroidectomy