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Clinical Trial Summary

The aim of this study is to evaluate the survival benefit of low-dose aspirin use for stage II-III esophageal cancer patients.


Clinical Trial Description

The investigators aimed to evaluate the hypothesis that low-dose aspirin can improve survival in stage II-III esophageal cancer patients, and to evaluate whether this effect is influenced by PIK3CA, KRAS, BRAF mutation and COX-2 expression. Eligible participants will be randomized to either aspirin treatment arm (100 mg aspirin OD for 3 years), or non-aspirin user arm in 1:1 ratio. After randomization, participants will receive 3 monthly assessments during treatment and follow-up. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02326779
Study type Interventional
Source Zhejiang University
Contact
Status Withdrawn
Phase Phase 3
Start date March 2016
Completion date December 2018

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