Study to Evaluate the Efficacy of Adalimumab in Patients With Erosive Osteoarthritis of the Interphalangeal Finger Joints

Erosive Osteo-Arthritis Clinical Trial

Official title: TNF-Blockade for the Treatment of Erosive Osteoarthritis (OA) of Interphalangeal Finger Joints: Randomized, Double Blind, Placebo-Controlled Cross-Over Study to Evaluate the Efficacy of Adalimumab 40 mg SC Every Other Week in Patients With Erosive Osteoarthritis of the Interphalangeal Finger Joints

Status Completed

Clinical Trial Summary

Patients will be randomized into two groups (1/1) during one year:

• 40 mg adalimumab subcutaneously (sc) every other week

• placebo

The effect on x-rays and clinical parameters will be evaluated.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Erosive Osteo-Arthritis
• Osteoarthritis

• NCT number: NCT00296894
• Study type: Interventional
• Source: University Hospital, Ghent
• Status: Completed
• Phase: Phase 2
• Start date: May 2006
• Completion date: February 2009