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NCT01830049 Clinical Trial

Differential Plasma MicroRNA Profiles in ED and Normal Erectile Function in Older Males

Erectile Dysfunction Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01830049
Other study ID # NJU2013024
Secondary ID 2013024
Status Recruiting
Phase N/A
First received April 9, 2013
Last updated April 10, 2013
Start date March 2013
Est. completion date August 2013

Study information
Verified date April 2013
Source Nanjing Medical University
Contact Feng Pan, Doctor
Phone 0086-25-52226379
Email panfeng27@yahoo.com.cn
Is FDA regulated No
Health authority China: Ethics Committee
Study type Observational

Clinical Trial Summary

Erectile dysfunction (ED) is strongly associated with aging. With the rapidly expanding aging population and the increase in life expectancy, an increase in the prevalence of ED is expected in the years to come. Currently, the mechanism of ED is not fully understood. MicroRNAs (MiRNA) are endogenous small RNA molecules that control gene expression post-transcriptionally. It has been included in many in vitro physiology and pathophysiology processes, which also involved in the process of ED. This research was designed to investigate the differential plasma MiRNA profiles in ED and normal erectile function in older males. The results might tell us which MiRNA and how did it involved in the process of ED in aging.

Recruitment information / eligibility
Status Recruiting
Enrollment 30
Est. completion date August 2013
Est. primary completion date July 2013
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 20 Years to 80 Years
Eligibility Inclusion Criteria:

- older males with erectile dysfunction

Exclusion Criteria:

- have some other general diseases, e.g. hypertension, vascular diseases, depression, chronic kidney disease, diabetes.

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Intervention

Other:
• Take blood

Locations
Country Name City State
China Nanjing Gulou Hospital affiliated to Nanjing University, Medical School Nanjing Jiangsu

Sponsors (1)
Lead Sponsor Collaborator
Nanjing Medical University

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary Gene chips 30 days Yes
Secondary RT-PCR 15 days Yes
See also
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Completed NCT00667979 - Evaluating the Efficacy of Vardenafil in Subjects With Erectile Dysfunction (ED) Administered 12, 18 or 24 Hours Prior to Intercourse Phase 4
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