Epithelial Ovarian Cancer Clinical Trial
Official title:
A Phase I/II Clinical Trial to Evaluate Platinum-based Chemotherapy, Oregovomab and Nivolumab in Patients With Platinum Sensitive Recurrent Epithelial Cancer of Ovarian, Tubal or Peritoneal Origin
This is an open-label, single-arm, phase I/II, single-center study with dose finding and dose expansion parts. This study hypothesizes that the combination of platinum-based chemotherapy, Oregovomab and Nivolumab will improve intracellular CA 125 antigen processing and elicit a stronger systemic CA 125-specific T cell response and that it will be in a manner that is synergistic, safe and clinical efficacious in patients with relapsed platinum sensitive epithelial ovarian carcinoma (EOC).
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|---|---|---|---|
| Active, not recruiting |
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Phase 1 | |
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N/A | |
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Phase 1 | |
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Phase 2 | |
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Phase 2 | |
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Phase 2 | |
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Phase 2 | |
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Phase 1 |