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Epistaxis clinical trials

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NCT ID: NCT04426409 Completed - Intubation Clinical Trials

Nasal Ointment on Epistaxis of Nasotracheal Intubation in Children

Start date: July 8, 2020
Phase: N/A
Study type: Interventional

Nasotracheal intubation is one of the anesthetic procedures required for oral surgery. It allows the surgeon easier access to the surgical site than the orthotracheal intubation. Therefore, nosotracheal intubation is commonly used for general anesthesia for oral and maxillofacial surgery and dental treatment. However, nasotracheal intubation can damage the nasal mucosa in the course of the tube passing through the nostrils, causing epistaxis which is reported as the most common side effect. In order to reduce these side effects, heating of the tube and use of a tube lubricant immediately before intubation have been recommended in children. However, research on whether the dry state of the mucosa itself contributes to the development of epistaxis is limited. A study in adults reported that pretreatment of the ointment on the mucosa reduced the damage to the mucosa. However, its effect on the incidence of epistaxis in children has not been studied. The purpose of this study is to investigate the effects of pretreatment of nasal ointment on epistaxis of nasotracheal intubation in children.

NCT ID: NCT04374448 Not yet recruiting - Chronic Sinusitis Clinical Trials

Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery

NIRFICG
Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The endoscope is a device placed into the nasal cavity to remove chronic sinus disease or tumor or create access into the skullbase for extensive tumor removal. Indocyanine Green (ICG) is a dye that is injected through an intravenous site and is used to light up vasculature and margins of a tumor during surgery. This helps avoid damage to important vasculature and obtain clear margins during surgery. This study aims to further assess the utility of ICG when operating within the nasal cavity or skullbase.

NCT ID: NCT04279288 Completed - Epistaxis Clinical Trials

The Roles of Hilotherapy in the Management of Epistaxis and Nasal Fractures

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The Investigators aimed to assess primarily whether or not Hilotherapy masks are a tolerable treatment for the conservative management of epistaxis and nasal fractures.

NCT ID: NCT04217941 Completed - Epistaxis Clinical Trials

Effect of Practical Demonstration to Use Nasal Spray and Apply Intranasal Ointment on Epistaxis

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

To compare the result of verbally educating the parents about method of intranasal antiseptic cream application versus practically educating and demonstrating how to apply cream intra nasally.

NCT ID: NCT04167085 Completed - Epistaxis Clinical Trials

NOrth American Study for the Treatment of Recurrent epIstaxis With DoxycycLine: The NOSTRIL Trial

NOSTRIL
Start date: December 18, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to determine whether Doxycycline can be used to control nosebleeds (epistaxis) for patients with Hereditary Hemorrhagic Telangiectasia (HHT). Patients with HHT will be randomized to one of 2 study arms: Doxycycline or Placebo for a period of 2 months followed by a 1-month washout period before switching treatments for a further 2 months period. Observation and evaluation will continue for a period of one month after treatment is completed.

NCT ID: NCT04164836 Completed - Clinical trials for Nasotracheal Intubation

Effect of Nose Selection Using Rhnoscope on Epistaxis of Nasotracheal Intubation

Start date: November 26, 2019
Phase: N/A
Study type: Interventional

Rhinoscope is useful to exam intranasal structure. This information could be utilized to select more suitable nose for nasotracheal intubation. Nastoracheal intubation using more patent nose could be associated with decrease of the development of epistaxis which is most common complication in nasotracheal intubation.

NCT ID: NCT04151888 Not yet recruiting - Epistaxis Clinical Trials

Hot Water Irrigation in Posterior Epistaxis

Start date: January 30, 2020
Phase:
Study type: Observational

This study was aimed to assess the efficacy and factors affecting the success of hot water irrigation in management of posterior epistaxis.

NCT ID: NCT04139018 Completed - Clinical trials for Hereditary Hemorrhagic Telangiectasia

Timolol Gel for Epistaxis in Hereditary Hemorrhagic Telangiectasia

ETIC-HHT
Start date: October 20, 2019
Phase: Phase 2
Study type: Interventional

This study is a double-blinded, randomized controlled trial to evaluate the efficacy of an intranasal topical timolol gel in the care for epistaxis in adults with hereditary hemorrhagic telangiectasia.

NCT ID: NCT04113187 Completed - Clinical trials for Hereditary Hemorrhagic Telangiectasia

Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia Patients

EPERO
Start date: June 23, 2020
Phase: Phase 3
Study type: Interventional

Hereditary Hemorrhagic Telangiectasia (HHT) is a genetic disorder of angiogenesis associated with disabling epistaxis. Management of these nose bleedings requires more effective treatment. Propranolol, a beta-blocker, is a potentially useful therapeutic considering its anti-angiogenic properties. Our objective is to explore the efficacy of propranolol, three months after its introduction, on the cumulative duration of epistaxis in HHT patients.

NCT ID: NCT04054687 Suspended - Epistaxis Clinical Trials

Intranasal TXA for Anterior Epistaxis in the Emergency Department

Start date: November 7, 2019
Phase: Phase 2
Study type: Interventional

The objective of this study is to evaluate the efficacy of and patient satisfaction with the use of intranasal tranexamic acid (TXA) for anterior nosebleeds in the emergency department (ED).