Implicit Learning in Epileptic Children

Epilepsy Clinical Trial

— IMPLICIT  

Official title:

Implicit Learning in Epileptic Children

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05285059
• Other study ID #: 69HCL21_1190
• Status: Recruiting
• Start date: March 21, 2023
• Est. completion date: March 21, 2026

Study information

• Verified date: March 2023
• Source: Hospices Civils de Lyon
• Contact: Marcastel Agathe, PhD
• Phone: +33 4 27 85 60 40
• Email: Agathe.marcastel[@]chu-lyon.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Epileptic children suffer from impairments in various learning and memory tasks. Yet, no study investigated implicit learning in epileptic children. Implicit learning is not only underlying motor skills acquisition, but also social and cognitive ones. Because acquisition of new skills is optimal during childhood, the study of implicit learning mechanism in children is of major importance. The present study will be the first to explore implicit learning mechanisms in children with epilepsy. Implicit learning mechanisms can be preserved or altered.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 40
• Est. completion date: March 21, 2026
• Est. primary completion date: March 21, 2026
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 8 Years to 14 Years

Eligibility

Inclusion Criteria:

• For Patient group only: Children with epilepsy

• For Control group only: Children without neurological, psychiatric or developmental impairments

• For both groups: Parent or tutors agreement

• For both groups: Affiliated to French social security

Exclusion Criteria:

• Neurological impairments unrelated to epilepsy

• Psychiatric impairments unrelated to epilepsy

• Developmental impairments unrelated to epilepsy

Related Conditions & MeSH terms

• Epilepsy

Intervention

Behavioral:
• ASRT task
The ASRT (Alternating Serial Reaction Time) task is a computerized behavioral task measuring implicit learning. This task consists of 20 series of trials lasting 2 minutes each. In each trial, a stimulus is displayed on the screen in one of the four possible predefined locations. The participant must press a button to indicate the position of the stimulus on the screen. Response content and response time are recorded. At the end of every trial, the participant can take a break and resume the task whenever ready. The task lasts about 45 to 50 minutes.

Locations

Country	Name	City	State
France	Agathe Marcastel, PhD	Bron
France	Dezso Nemeth	Bron
France	Service d'Epileptologie Clinique, des Troubles du sommeil et de Neurologie fonctionnelle de l'enfant, à Hôpital Femme Mère et Enfant,	Bron

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Response time	Response time (in milliseconds) recorded during the ASRT task	The day of the inclusion
Primary	Response accuracy recorded during the ASRT task	Response accuracy (percentage of correct answers)	The day of the inclusion