Fecal Microbiota Transplantation for Epilepsy

Epilepsy Clinical Trial

Official title: Efficacy and Safety of Fecal Microbiota Transplantation for Epilepsy

Status Recruiting

Clinical Trial Summary

Increasing evidences showed the microbiota effects on neuropsychiatric disorders. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation for epilepsy.

Clinical Trial Description

Very few literatures reported the clinical use of microbiota or bacteria for brain diseases. The most effective strategy for reconstruction of gut microbiota should be fecal microbiota transplantation (FMT). This study aims to evaluate the efficacy and safety of FMT for epilepsy. Patients were diagnosed as epilepsy by electroencephalogram (EEG) and MRI and clinical data when the study began and thent received repeated FMT with fecal from healthy donors.The antiepileptic medication regimen of patients remained unchanged after FMT. The primary outcome measure was the frequency of the seizures. Secondary outcome measure were the 50% response rate.

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Related Conditions & MeSH terms

• Epilepsy

• NCT number: NCT02889627
• Study type: Interventional
• Source: The Second Hospital of Nanjing Medical University
• Contact: Faming Zhang, MD,PhD
• Phone: 086-25-58509883
• Email: fzhang@njmu.edu.cn
• Status: Recruiting
• Phase: Phase 2/Phase 3
• Start date: November 2016
• Completion date: December 2025