Epilepsy Clinical Trial
Official title:
Epilepsy Phenome/Genome Project: A Phenotype/Genotype Analysis of Epilepsy
The purpose of this study is to collect detailed information about the characteristics and genetics of a large number of individuals with epilepsy.
Epilepsy is one of the most common neurological disorders and is a major public health
concern. Approximately 30 percent of people with epilepsy have medically intractable
epilepsy, and the medical and social consequences of the disorder are enormous. Treatments
developed for epilepsy have largely been experimental rather than based on knowledge of basic
mechanisms because the mechanisms are poorly understood.
The Epilepsy Phenome/Genome Project (EPGP) is a large-scale, international,
multi-institutional, collaborative research project aimed at advancing the understanding of
the genetic basis of the most common forms of epilepsy.
The overall goal of EPGP is to collect detailed, high quality phenotypic (i.e.,
characteristics of individuals, from the molecular level to the whole person) information on
persons with epilepsy and to compare the phenotypic information with genomic information.
EPGP will provide a resource that may lead to many discoveries related to the diagnosis and
treatment of epilepsy, including the eventual development of new therapies based on a better
understanding of causes of the disorder.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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| Completed |
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N/A | |
| Completed |
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|
||
| Completed |
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N/A | |
| Completed |
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| Active, not recruiting |
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N/A | |
| Recruiting |
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||
| Not yet recruiting |
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N/A | |
| Not yet recruiting |
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|
||
| Completed |
NCT02977208 -
Impact of Polymorphisms of OCT2 and OCTN1 on the Kinetic Disposition of Gabapentin in Patients Undergoing Chronic Use
|
Phase 4 | |
| Completed |
NCT02952456 -
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||
| Completed |
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N/A | |
| Recruiting |
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Phase 1 | |
| Completed |
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N/A | |
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|
N/A |