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Epilepsies, Partial clinical trials

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NCT ID: NCT00231556 Completed - Epilepsy Clinical Trials

A Study on Safety and Efficacy of Two Doses of Topiramate as Monotherapy in the Treatment of Newly Diagnosed or Recurrent Epilepsy

Start date: July 1999
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of two doses of topiramate as monotherapy in the treatment of pediatric and adult patients with newly diagnosed or recurrent epilepsy.

NCT ID: NCT00230698 Completed - Epilepsy Clinical Trials

A Study of the Effectiveness and Safety of Topiramate Monotherapy in Patients With Recently Diagnosed Partial-Onset Seizure

Start date: November 1995
Phase: Phase 3
Study type: Interventional

The purposes of this study are (1) to compare the effectiveness of two doses of topiramate and (2) to assess the safety of topiramate alone in the treatment of pediatric and adult patients with recently diagnosed epilepsy characterized by partial-onset seizures.

NCT ID: NCT00215215 Terminated - Epilepsies, Partial Clinical Trials

Effectiveness Study Comparing Treatment With Drug(s) or Adjunctive VNS Therapy for Pharmacoresistant Partial Seizures

Start date: February 2005
Phase: Phase 4
Study type: Interventional

To compare outcomes over 12 months of treatment with antiepileptic drugs (AEDs) alone or vagus nerve stimulation (VNS) therapy plus AEDs in patients who have partial seizures refractory to at least two, but not more than five, AEDs.

NCT ID: NCT00212745 Completed - Epilepsies, Partial Clinical Trials

Pilot Trial of a Behavioral Treatment for Epilepsy

Start date: February 2004
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this research study is to see if a behavioral program which includes a relaxation technique and lifestyle changes can improve seizure control and well-being in epilepsy patients.

NCT ID: NCT00210652 Completed - Epilepsy Clinical Trials

An Open-Label Extension Study to Evaluate the Safety and Effectiveness of RWJ 333369 in Patients With Epilepsy

Start date: July 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and preliminary effectiveness of the novel compound RWJ-333369 in patients with partial onset seizures who are currently being treated with 1 or 2 concomitant antiepileptic drugs.

NCT ID: NCT00210522 Completed - Epilepsy Clinical Trials

An Open-Label Extension Study of the Effectiveness and Safety of the Investigational Compound RWJ-333369 in Patients With Epilepsy

Start date: May 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and safety of the novel compound RWJ-333369 in reducing the frequency of seizures in patients with epilepsy.

NCT ID: NCT00175929 Completed - Epilepsy, Focal Clinical Trials

A Study of Brivaracetam in Subjects With Partial Onset Seizures

Start date: May 2005
Phase: Phase 2
Study type: Interventional

This trial will evaluate the efficacy and safety of brivaracetam (at doses of 50 and 150 mg/day in twice a day administration) as add on therapy in subjects with focal epilepsy

NCT ID: NCT00175890 Completed - Epilepsy, Partial Clinical Trials

A Placebo-controlled Study of Levetiracetam In Children (1mo to 4yrs of Age) With Partial Onset Seizures.

Start date: October 2004
Phase: Phase 3
Study type: Interventional

To evaluate the safety and efficacy of levetiracetam used as adjunctive treatment in pediatric subjects age 1 month to less than 4 years with partial onset seizures. Subjects will be evaluated with 48 hour inpatient video electroencephalograms (a selection and an evaluation). Other neuropsychological clinical assessments will be performed during the 34 day length of the study.

NCT ID: NCT00160654 Completed - Epilepsy, Partial Clinical Trials

Open Label Safety and Efficacy Study of Levetiracetam in Patients With Epilepsy

Start date: November 24, 2003
Phase: Phase 4
Study type: Interventional

Community based study assessing safety and efficacy of levetiracetam in partial onset seizures. The optimal dose in daily clinical practice will be used.

NCT ID: NCT00160628 Completed - Epilepsy, Partial Clinical Trials

Open Label Safety and Efficacy Study of Levetiracetam in Korean Patients With Epilepsy

Start date: March 2004
Phase: Phase 3
Study type: Interventional

A Korean open-label, community-based trial assessing the efficacy and safety of levetiracetam as adjunctive therapy in partial epilepsy. Similarity with a similar study conducted in Caucasian epileptic subjects will be assessed.