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Enteritis clinical trials

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NCT ID: NCT03516461 Recruiting - Radiation Enteritis Clinical Trials

Microbiota Transplantation for Radiation Enteritis

Start date: January 7, 2018
Phase: N/A
Study type: Interventional

Radiation enteritis is one of the most feared complications after abdominal or pelvic radiation therapy.The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body metabolism. Evidence from animal studies demonstrated the link between intestinal bacteria and radiation enteritis. This clinical trial aims to evaluate the efficacy and safety of selective microbiota transplantation (SMT) and fecal microbiota transplantation (FMT) for radiation enteritis.

NCT ID: NCT03444675 Recruiting - Clinical trials for Transplant; Complication, Rejection

The Endoscopic Assesment of Intestinal Grafts

INTEGRATE
Start date: April 29, 2014
Phase:
Study type: Observational

The study validates prospectively a new endoscopic scoring system (Gothenburg Intestinal Transplant Endoscopy Score, GITES) designed to summarize and stratify the abnormal ileal endoscopic findings after intestinal transplantation. GITES is a five-tier, four grade score which asseses mucosal friability, mucosal erythema and mucosal injury (ulcerations) as well as villous changes according to severity. These features (i.e., endoscopic descriptors) are also grouped from mild to very severe in the same sequence as observed during the progression of several pathologic conditions encountered after intestinal transplantation (acute rejection, infectious enteritis).

NCT ID: NCT02523118 Recruiting - Clinical trials for Eosinophilic Esophagitis

OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

OMEGA
Start date: July 17, 2015
Phase:
Study type: Observational

The purpose of this observational study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EG, EGE and EC normally undergo endoscopy and/or colonoscopy where cells are collected for microscopic analysis. Treatments are then decided based on how the cells look. We are aiming to compare different tissue components such as inflammatory cell types with clinical symptoms. We want to see if scores on standard questionnaires can give us an idea how well the person is doing.

NCT ID: NCT01414517 Recruiting - Radiation Enteritis Clinical Trials

Study to Prevent Radiation Induced Damage to Bowel Using a Prebiotic Enhanced Diet.

Start date: August 2010
Phase: Phase 3
Study type: Interventional

The study will consist of pair of double-blind placebo-controlled trials of dietary supplementation with 15g/day FructoOligoSaccharide (FOS) for 7.5 weeks in patients with prostate carcinoma or 5 weeks in patients with cervical or endometrial carcinoma who are to undergo pelvic radiotherapy with intent to cure.

NCT ID: NCT01113346 Recruiting - Clinical trials for Viral Gastroenteritis

A Pilot Study of Filtrum-STI in Children With Viral Gastroenteritis

F-GE-09
Start date: June 2010
Phase: Phase 2/Phase 3
Study type: Interventional

This is a phase II double blind multicenter randomized placebo-controled clinical study aimed to find out whether treatment with Filtrum-STI (orally administered 0,4g tablets) is safe and effective in children with viral gastroenteritis. Filtrum-STI (lignin hydrolytic) is a drug with a high absorbing ability, that binds and eliminates toxins, pathogenic microorganisms and viruses. Filtrum-STI is inoffensive for mucous membranes, enhances colonic propulsion and improves its natural microflora. The drug is not toxic and well combines with other medication

NCT ID: NCT01065324 Recruiting - Bleeding Clinical Trials

Balloon-assisted Enteroscopy and Bacteria

Start date: February 2010
Phase: N/A
Study type: Observational

1. Balloon-assisted enteroscopy (BAE) is a new tool to investigate small intestinal diseases. 2. Deep enteroscopy made possible by balloon expansion and manipulation of small intestines. 3. However, whether intestinal barrier injured during BAE predispose patients to bacteremia or clinical relevant infection is not studied. 4. We will also examine relevant patient factors.