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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT06163456
Other study ID # 1810041426
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date December 2, 2019
Est. completion date November 29, 2023

Study information

Verified date November 2023
Source Towson University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This research is being done to determine whether acute exercise causes differences in numbers of novel blood factors associated with vascular health in college-aged adults across different physical activity habits. As only ~50% of cardiovascular (CV) events can be explained by traditional CV risk factors such as high blood pressure and high cholesterol, it is anticipated that this research will provide a more comprehensive look into novel risk factors that may better explain CV risk and that may be modifiable through regular physical activity.


Recruitment information / eligibility

Status Completed
Enrollment 43
Est. completion date November 29, 2023
Est. primary completion date March 15, 2020
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 29 Years
Eligibility Inclusion Criteria: - 18-29 years of age; healthy male and female; Physically inactive, defined as participation in less than 20 min of continuous endurance exercise on fewer than 2 days/week; Recreationally active, defined as participation in 30 min/day of moderate-intensity cardiovascular activity on greater than 4 days/week; Highly active- defined as performing 30-60 min of moderate- to vigorous-intensity endurance exercise greater than 5 days/week. Exclusion Criteria: - currently pregnant, previously diagnosed coronary heart disease or congenital heart disease, serum total cholesterol >200 mg/dl, low-density lipoprotein cholesterol >130 mg/dl, high-density lipoprotein cholesterol < 35 mg/dl, fasting glucose >100 mg/dl, systolic blood pressure > 130 mmHg, diastolic blood pressure >90 mmHg, and BMI >30 kg/m2.

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Acute submaximal exercise
30 min of treadmill running at 70% of the participants maximal oxygen consumption

Locations

Country Name City State
United States Towson University Towson Maryland

Sponsors (1)

Lead Sponsor Collaborator
Towson University

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Primary endothelial function flow-mediated dilation Baseline and 60 min post-exercise
Primary arterial stiffness augmentation index Baseline and 60 min post-exercise
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