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NCT01729234 Clinical Trial

Effects of Dietary Nitrate on Age-related Vascular Function

Endothelial Dysfunction Clinical Trial

Official title:
Effects of Dietary Nitrate Supplementation on Age-related Vascular Dysfunction

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01729234
Other study ID # Nitrate for vascular age
Secondary ID
Status Completed
Phase Phase 1/Phase 2
First received November 14, 2012
Last updated December 6, 2013
Start date October 2012
Est. completion date May 2013

Study information
Verified date December 2013
Source Heinrich-Heine University, Duesseldorf
Contact n/a
Is FDA regulated No
Health authority Germany: Federal Institute for Drugs and Medical Devices
Study type Interventional

Clinical Trial Summary

Purpose of the study is to characterize the chronic effect of dietary nitrate on vascular function in healthy volunteers with particular emphasis on age-related alterations.

Recruitment information / eligibility
Status Completed
Enrollment 20
Est. completion date May 2013
Est. primary completion date May 2013
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 55 Years and older
Eligibility Inclusion Criteria:

>55 Years Healthy

Exclusion Criteria:

known cardiovascular disease

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention

Related Conditions & MeSH terms

Intervention

Dietary Supplement:
• Nitrate
Dietary Supplement
• Placebo
Dietary Supplement

Locations
Country Name City State
Germany Heinrich-Heine-University Duesseldorf, Nrw,

Sponsors (1)
Lead Sponsor Collaborator
Heinrich-Heine University, Duesseldorf

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Endothelial function measured by flow-mediated dilation (FMD) The effect of dietary nitrate on endothelial function as measured by flow-mediated dilation (FMD) after forearm ischemia and reperfusion. 30 days No
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