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BMD Alterations and Bone and Muscle Parameters During Menstrual Cessation With GnRH

Endometriosis Clinical Trial

Official title:
Bone Mineral Density Alterations and Correlations With Bone and Muscle Metabolism Parameters During Menstrual Cessation Due to GnRH Therapy and After Menstrual Restoration

Clinical Trial Summary

The investigators aim to investigate the effect of menstrual cessation in women with endometriosis treated with GnRH analogs for 6 months on bone mineral density and bone and muscle metabolism parameters and subsequently the effects of menstrual restoration after GnRH analogs discontinuation on the above measured parameters

Clinical Trial Description

Prospective, open-label, controlled 12month observational study Premenopausal women with surgically verified endometriosis will receive goserelin 1 injection per month for 6 months. Subsequently goserelin will be discontinued and patients will be monitored for another 6 months after menstrual restoration. Age- and BMI-matched premenopausal, health women will serve as controls. Controls will receive no treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04203212
Study type Observational
Source 424 General Military Hospital
Contact
Status Completed
Phase
Start date October 1, 2019
Completion date December 31, 2020
View Details
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