Endometriosis Clinical Trial
Official title:
Fertility Preservation in Case of Endometriosis : Observational Cohort Study
Fertility Preservation is now considered as crucial for the well-being of women battling
cancer. However, others indications have more recently emerged. Women with endometriosis may
represent a suitable group since they are at risk for compromise ovarian reserve. Data on FP
in endometriosis patients are rare: only small retrospective study, case-reports and opinion
publications .Nowadays, there is no available data concerning real indications for PF on
endometriosis patients (endometriomas, risk of surgery, deep endometriosis?), criteria for
eligibility (ovarian reserve parameters, age), quality of oocytes and number of oocytes
necessary to give at least one live birth.
We propose a monocentric observational cohort study, evaluating the efficacy of oocytes
cryopreservation as fertility preservation procedure, in young adult female subjects with
endometriosis, to finally define the criteria of eligibility for PF procedures in case of
endometriosis.
Monocentric observational cohort study, enrolling young patients with endometriosis, without
birth project for the moment, and asking for fertility preservation, in order to preserve
mature oocytes.
Protocol of this study :
- information and signatures of consent file ;
- ovarian stimulation, oocytes retrieval and mature oocytes cryopreservation (one or more
procedures)
- questionnaires every year, describing quality of life in this context of endometriosis
and evolution (treatment, surgery, ART, pregnancies)
- data about number and rate of thawed oocytes after preservation, pregnancy rate and live
birth rate with these oocytes.
;
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