Clinical Trials Logo

Endometriosis clinical trials

View clinical trials related to Endometriosis.

Filter by:

NCT ID: NCT03411980 Completed - Endometriosis Clinical Trials

Pharmacokinetics and Safety of Vilaprisan in Renal Impairment

Start date: February 2, 2018
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the pharmacokinetics of vilaprisan in subjects with moderate to severe renal impairment compared with matched subjects with normal renal function.

NCT ID: NCT03376451 Recruiting - Blood Biomarkers Clinical Trials

EndoSearch : Endometriosis Biomarkers

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

EndoSearch aims to analytically validate a cluster of specific biomarkers for endometriosis diagnosis and disease recurrence. This signature will be tested on endometrium and blood from 975 patients, divided in two groups : 550 patients affected by endometriosis and 225 patients unaffected (controls). EndoSearch is not about drug or medical device assessment but a research study for biomarker analytical validation purpose.

NCT ID: NCT03373422 Terminated - Endometriosis Clinical Trials

A Study to Test Whether Study Drug BAY1128688 Brings Pain Relief to Women With Endometriosis and if so to Get a First Idea Which Dose(s) Work Best

AKRENDO1
Start date: November 30, 2017
Phase: Phase 2
Study type: Interventional

Purpose of the study is to test whether study drug BAY1128688 brings relief for pain to women with endometriosis and if so to get a first impression which dose(s) work best.

NCT ID: NCT03354793 Completed - Endometriosis Clinical Trials

Endometriosis and Risk of Obstetric Complications

Start date: January 15, 2016
Phase: N/A
Study type: Observational

The aim of this study is to compare the rate of obstetric complications at first spontaneous pregnancy among women with endometriosis, with the rate of obstetric complications at first spontaneous pregnancy among women without endometriosis

NCT ID: NCT03354780 Completed - Endometriosis Clinical Trials

Endometriosis and Risk of Miscarriage

Start date: January 15, 2016
Phase: N/A
Study type: Observational

The aim of this study is to compare the rate of miscarriage at first spontaneous pregnancy among women with endometriosis with the rate of miscarriage at first spontaneous pregnancy among women without endometriosis.

NCT ID: NCT03353935 Completed - Endometriosis Clinical Trials

Functional Outcomes After Nerve Sparing Surgery for Deep Endometriosis

Start date: January 2016
Phase: N/A
Study type: Observational

Patients who underwent surgery for deep endometriosis were submitted to procedures aiming at sparing the pelvic autonomic nervous system. They were observed prospectively followed and interviewed in order to evaluate functional outcomes after surgery.

NCT ID: NCT03352661 Active, not recruiting - Endometriosis Clinical Trials

Influence of an Endometrioma on Oocyte Quality

ENDOVOC
Start date: January 2017
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate if there are differences in oocyte quality depending on whether these oocytes come from an ovary in contact with an endometrioma.

NCT ID: NCT03352076 Completed - Endometriosis Clinical Trials

Study to Determine Intraperitoneal,Tissue, Serum Concentrations of VML-0501 Following Five Days of Daily Vaginal Single Dose of VML-0501 (100 mg Danazol), in Comparison to Oral Danazol Capsules Daily 600 mg), in Women With Signs and Symptoms of Endometriosis Undergoing Laparoscopy

Start date: December 28, 2017
Phase: Phase 2
Study type: Interventional

A Comparative, Open-Label, Randomized, Parallel Group Study to determine Intraperitoneal fluids, tissue, and serum concentrations of VML-0501 following five days of daily vaginal applications of single dose of VML-0501 (100 mg Danazol), in comparison to five days of Danazol treatment administered as an oral capsule (Danatrol) at a daily dose of 600 mg, in two groups of twelve each consisting of women with suspected or confirmed endometriosis and scheduled for laparoscopy.

NCT ID: NCT03343067 Terminated - Endometriosis Clinical Trials

A Study to Evaluate Safety and Efficacy of Elagolix in Participants With Endometriosis With Associated Moderate to Severe Pain

Start date: December 27, 2017
Phase: Phase 3
Study type: Interventional

This is a Phase 3, dose-escalation study designed to evaluate the safety and efficacy of both elagolix alone and elagolix plus estradiol/norethindrone acetate (E2/NETA) over 24 months in the management of endometriosis with associated moderate to severe pain in premenopausal women.

NCT ID: NCT03340324 Recruiting - Endometriosis Clinical Trials

Open Label Immunotherapy of Endometriosis

Start date: October 1, 2017
Phase: Phase 2
Study type: Interventional

Endometriosis is a chronic gynecological disease characterized by sustained painful symptoms that are responsible for a decline in the quality of life of sufferers. Endometriosis is fairly common, affecting an estimated 10%-15% of women and girls, usually during their reproductive years. Based on these rough estimates, the latest epidemiological studies suggest that over 200 million women are might be affected who may commonly have infertility problems. Additionally, endometriosis is a major factor increasing by 33-66% risk of ovarian cancer. V-Endo is a tableted preparation derived from hydrolyzed, heat-inactivated, pooled blood of women with endometriosis. When taken orally it is postulated to cause the immune tolerance and anti-inflammatory effect as a result.