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Endometrial Polyp clinical trials

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NCT ID: NCT06324851 Completed - Clinical trials for Endometrial Diseases

The Use of Drospirenone/Estetrol, Nomegestrol Acetate/Estradiol and Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation

Start date: January 1, 2023
Phase: Phase 4
Study type: Interventional

The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety of drugs. We explored the efficacy of random started 14-day administration of Drospirenone/Estetrol or Nomegestrol Acetate/Estradiol or Ethinylestradiol/Dienogest, in rapid preparation of endometrium for hysteroscopic polypectomy.

NCT ID: NCT06316219 Completed - Clinical trials for Endometrial Diseases

The Use of Nomegestrol Acetate/Estradiol in Random Start Rapid Endometrial Preparation

Start date: January 1, 2023
Phase: Phase 4
Study type: Interventional

The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety of drugs. We explored the efficacy of random started 14-day administration of Nomegestrol Acetate/Estradiol, in rapid preparation of endometrium for hysteroscopic polypectomy.

NCT ID: NCT06316206 Completed - Clinical trials for Endometrial Diseases

The Use of Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation

Start date: January 1, 2023
Phase: Phase 4
Study type: Interventional

The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety of drugs. We explored the efficacy of random started 14-day administration of Ethinylestradiol/Dienogest, in rapid preparation of endometrium for hysteroscopic polypectomy.

NCT ID: NCT06316180 Completed - Clinical trials for Endometrial Diseases

The Use of Drospirenone/Estetrol in Random Start Rapid Endometrial Preparation

Start date: January 1, 2023
Phase: Phase 4
Study type: Interventional

The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety of drugs. We explored the efficacy of random started 14-day administration of drospirenone/estetrol, in rapid preparation of endometrium for hysteroscopic polypectomy.

NCT ID: NCT05337605 Completed - Endometrial Polyp Clinical Trials

Hand Driven Versus Motor Driven Hysteroscopic Tissue Removal System for Polypectomy: Long-term Results

Start date: April 1, 2022
Phase:
Study type: Observational [Patient Registry]

In this study, a comparison is made between two types of polyp resection methods (hand driven and motor driven morcellation). More specifically, the effects of the resection on symptoms such as abnormal uterine bleeding, and on the recurrence of polyps. The aim of the study is to find a superior method in terms of symptom relieve and polyp recurrence so this method can be used in gynaecological practice.

NCT ID: NCT05337046 Completed - Endometrial Polyp Clinical Trials

Hysteroscopic Tissue Removal System Versus Bipolar Resectoscopy for Polypectomy: Long-term Results

Start date: April 1, 2022
Phase:
Study type: Observational [Patient Registry]

In this study, a comparison is made between two types of polyp resection methods (hysteroscopic tissue removal and bipolar resectoscopy). More specifically, the effects of the resection on symptoms such as abnormal uterine bleeding, and on the recurrence of polyps. The aim of the study is to find a superior method in terms of symptom relieve and polyp recurrence so this method can be used in gynaecological practice.

NCT ID: NCT04706000 Completed - Endometrial Polyp Clinical Trials

Autophagy Markers in Endometrial Polyps

Start date: January 8, 2021
Phase:
Study type: Observational

The aim of this research is to evaluate autophagy markers in patients with endometrial polyps

NCT ID: NCT03790215 Completed - Endometrial Polyp Clinical Trials

Dydrogesterone in the Treatment of Endometrial Polyps

Start date: February 1, 2019
Phase: Phase 4
Study type: Interventional

This study is intended to observe the therapeutic effect of dydrogesterone on endometrial polyps and provide a reference for clinical treatment.

NCT ID: NCT02520414 Completed - Uterine Leiomyomas Clinical Trials

Symphion® System In-Office Study

Start date: November 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the safety and feasibility of using the Symphion system in an office setting.

NCT ID: NCT02472197 Completed - Endometrial Polyps Clinical Trials

Morcellator Versus Resectoscope in the Treatment of Uterine Polyps by Hysteroscopy

RESMO
Start date: September 2015
Phase: N/A
Study type: Interventional

Intrauterine pathologies are currently treated by hysteroscopic resection. In this surgical procedure, the intrauterine pathology is resected by a transcervical approach in several fragments using a mono or bipolar cove after distension of the uterine cavity and by endoscopic control. The main risks of this surgery are: uterine perforation and OHIA (operative hysteroscopy intravascular absorption) syndrome. Hysteroscopic morcellators are new intrauterine devices, recently appeared on the French market. In comparison to classical resectors, morcellators have several theoretical advantages: - A smaller instrument diameter with potentially a lower risk of uterine perforation and cervical laceration during the dilatation procedure, - The use of physiological serum, eliminating the risk of neurological toxicity of glycine, - The risk of electrical accident is canceled (internal or external burns due to leakage current), - A decreased risk of air embolism, due to the absence of bubbles' production, - The instrument is always under visual control, the perforation risk by the active instrument is therefore very limited, - The vision is not obscured by the fragments or by the bubbles, - The treatment of pre-ostial pathologies, not always easy in classical resections, could be facilitated, - the absence of thermal effect, and therefore a potentially lower endometrial aggression, is interesting in women with reproductive desire, - Absence of chips management, limiting the entry and exit movements in the uterine cavity, improving the vision, reducing the infectious and traumatic risks, specially uterine perforation and air embolism, - Morcellation could preserve tissues for histological analysis of possible malignancy (compared to techniques using heat, coagulation, vaporization), - Easy learning in comparison to the time-consuming learning of classical hysteroscopic resection, - Generated additional cost could be partly amortized by reducing operating time and complications. It seemed useful to study this new technology. The primary purpose was to compare the time of hysteroscopic treatment of uterine polyps between a hysteroscopic morcellator the UNIDRIVE S III / DrillCut-X II-GYN-Shaver (Integrated Bigatti Shaver IBS), Storz®, and a conventional resectoscope. The secondary purposes were to compare the efficiency, complications and comfort of these techniques.