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Endometrial Hyperplasia clinical trials

View clinical trials related to Endometrial Hyperplasia.

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NCT ID: NCT04491682 Completed - Clinical trials for Atypical Endometrial Hyperplasia

Megestrol Acetate Plus Rosuvastatin in Young Women With Atypical Endometrial Hyperplasia

Start date: September 1, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

To see if megestrol acetate plus rosuvastatin will be superior to reversing the endometrial lesion to a normal endometrium than megestrol acetate alone in patients with atypical endometrial hyperplasia (AEH). Considering the large sample size in RCT, we used Simon two-stage design.

NCT ID: NCT04385667 Completed - Clinical trials for Atypical Endometrial Hyperplasia

LVN- IUS Versus Oral Megesterol Acetate in Treatment of Atypical Endometrial Hyperplasia

Start date: May 20, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

This randomized controlled trial is aimed to compare the efficacy between Megestrol acetate (MA) and the levonorgestrel intrauterine system (LNG-IUD) regarding the ability and duration to produce complete regression for cases with atypical endometrial hyperplasia.

NCT ID: NCT04362046 Recruiting - Endometrial Cancer Clinical Trials

Fertility Sparing Management of EndomeTrial Cancer and Hyperplasia

FETCH
Start date: November 15, 2020
Phase: N/A
Study type: Interventional

This study protocol evaluates the use of hysteroscopic endomyometrial resection in women diagnosed with atypical endometrial hyperplasia or grade I endometrial cancer who have not responded to anti-hormone therapy. Patients in this study wish to preserve fertility.

NCT ID: NCT04191603 Not yet recruiting - Cervical Dysplasia Clinical Trials

TWO DİFFERENT ELECTROSURGERY DEVICES AS MONOPOLAR HOOC AND PLASMAKINETIC BIPOLAR SPATULA EFFECTIVENESS DURING COLPOTOMY

Start date: October 30, 2020
Phase: N/A
Study type: Interventional

WE DECIDED TO COMPARE TWO DIFFERENT ELECTROSURGERY DEVİCES TO PROVIDE COLPOTOMY. ONE OF THEM İS MONOPOLAR HOOC, THE OTHER DEVİCE İS PLASMAKİNETİC BİPOLAR SPATULA. WE WİLL RANDOMİSE PATİENTS FİRSTLY THEN COMPARE THE RESULTS SUCH, VAGİNAL DEHİSSENS, COLPOTOMY DURATİON, AMOUNT OF MIST DURING COLPOTOMY, AMOUNT OF BLEEDİNG.

NCT ID: NCT03992937 Completed - Clinical trials for Endometrial Hyperplasia Without Atypia

Vaginal Micronized Progesterone Versus Levonorgestrel for Treatment of Non-atypical Endometrial Hyperplasia

Start date: June 20, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the efficacy of the vaginal micronized progesterone and Levonorgestrel-releasing Intrauterine System for treatment of non-atypical endometrial hyperplasia in premenopausal women.

NCT ID: NCT03972917 Completed - Dysmenorrhea Clinical Trials

Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy

Start date: November 1, 2018
Phase:
Study type: Observational

A prospective observational study on italian women undergoing ulipristal acetate (uPa) therapy for symptomatic myomas and its impact on symptomatology and moreover on myomas architecture. We also evaluate changes in the endometrial pattern of selected women.

NCT ID: NCT03965585 Completed - Infertility, Female Clinical Trials

Office Hysteroscopy in Infertility Work-out: the Role of Endometrial Hyperplasia in Southern Italian Women

Start date: January 2, 2019
Phase:
Study type: Observational

To assess the prevalence of endometrial hyperplasia (EH), endometrial intraepithelial neoplasia (EIN) and endometrial carcinoma between obese and not obese women undergoing IVF techniques for primary or secondary infertility.

NCT ID: NCT03917147 Completed - Clinical trials for Endometrial Neoplasms

Correlation Between Hysteroscopic Diagnosis of Endometrial Hyperplasia and Histopathological Examination

Start date: January 8, 2018
Phase:
Study type: Observational

A prospective cohort study at a Tertiary University Hospital. From January to December 2018, we enrolled women with the following criteria: abnormal uterine bleeding in post-menopause, endometrial thickening in pre-or post-menopause; tamoxifen usage. Patients underwent office hysteroscopy with a 5-mm continuous-flow hysteroscope and endometrial biopsies were taken using miniaturized instruments. Senior operators had to foresee histopathological diagnosis using a questionnaire. Histopathological examination was conducted to confirm the diagnosis.

NCT ID: NCT03675139 Completed - Clinical trials for Endometrial Hyperplasia Without Atypia

MPA Versus Dydrogesterone for Management of Endometrial Hyperplasia Without Atypia

Start date: February 26, 2019
Phase: Phase 3
Study type: Interventional

To compare the efficacy of Medroxyprogesterone Acetate with dydrogesterone in patients having endometrial hyperplasia (EH) without atypia.

NCT ID: NCT03671811 Active, not recruiting - Clinical trials for Endometrial Carcinoma

Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy

Start date: January 21, 2019
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well megestrol acetate with or without pterostilbene works in treating patients with endometrial cancer undergoing hysterectomy. Drugs used in chemotherapy, such as megestrol acetate, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Pterostilbene is an antioxidant found in blueberries or grapes, and it has been shown to be effective in killing tumor cells and reducing cancer burden. It is not yet known whether giving megestrol acetate with or without pterostilbene may work better in treating patients with endometrial cancer.