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NCT05793333 Clinical Trial

Predictors of Node Positivity in Endometrial Cancer

Endometrial Cancer Clinical Trial

Official title:
Histological and Molecular Characteristics Predict the Risk of Nodal Involvement in Endometrial Cancer: a Prospective Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05793333
Other study ID # 142020
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date August 10, 2023
Est. completion date December 31, 2023

Study information
Verified date July 2023
Source Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To investigate the role of histological and moleculr profile of endometrial cancer patietns in predicting the risk of nodal metastases in endoemtrila cancer patients.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 100
Est. completion date December 31, 2023
Est. primary completion date December 31, 2023
Accepts healthy volunteers
Gender Female
Age group 18 Years and older
Eligibility Inclusion Criteria: - Written informed consent - Histologically confirmed endometrila cancer - Data on molecular genomic profiling (POLE mutated, p53 abnormalities, MMRd/MSI-H, and NSMP) - Data on histological characteristics of the ttumor - Execution of sentinel node mapping - Data on sentinel node status (negative vs. positive) Exclusion Criteria: - Stage IVB endoemtrial cancer - consent withdraw

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Outcome
Type Measure Description Time frame Safety issue
Primary positive nodes positive nodes detected by sentinel node mappinig 12 months
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