Host DNA Methylation for Endometrial Cancer Screening

Status Recruiting

Clinical Trial Summary

Based on the previous study of NCT04651738, we performed this trial to further confirm the accuracy of host DNA CDO1 and CELF4 methylation for endometrial cancer screening in a multi-center cohort. Thirteen hospitals, including Peking Union Medical College Hospital, would enroll eligible patients in this study. The cervical cytology of 3 ml will be collected for the detection of DNA CDO1 and CELF4 methylation, and the results will compared with the endometrial histological pathology, which is achieved after collection of cervical cytology, by surgeries including hysteroscopy, dilation and curettage, total hysterectomy and others. The methylation testing would be double-blinded in operators and analysts. The study will enroll at least 10,000 patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05290415
Study type	Observational
Source	Peking Union Medical College Hospital
Contact	Lei Li, M.D.
Phone	10-139-1198-8831
Email	lileigh@163.com
Status	Recruiting
Phase
Start date	March 13, 2022
Completion date	September 13, 2022

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