Optimized vs. Standard Automated Peritoneal Dialysis Regimens Study

Status Completed

Clinical Trial Summary

This clinical study is designed to evaluate the theoretical prediction of a lower glucose absorption in optimized automated peritoneal dialysis regimes. Patients will receive both a standard 6 x 2L 1.36% glucose regime or an optimized 7 x 2 L 2.27% glucose + 5 x 2 L 0.1% glucose regime in a crossover fashion.

Clinical Trial Description

Automated peritoneal dialysis (APD) is a rapidly growing, home-based kidney replacement therapy promoting patient autonomy, and is associated with lower societal costs compared to hemodialysis. However, in light of the growing number of diabetic patients on PD, the unwanted glucose absorption during APD is problematic. Recent results (Öberg CM, Rippe B, 2017, see references), using a theoretical model of APD, indicate that large reductions in glucose absorption are possible by using specialized so-called optimized bi-modal treatment regimes having "UF cycles" using a higher glucose concentration (e.g. 2.27% glucose) and "Clearance cycles" using a low glucose concentration (e.g. 0.1% glucose). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04017572
Study type	Interventional
Source	Lund University
Contact
Status	Completed
Phase	N/A
Start date	June 1, 2019
Completion date	September 30, 2020

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Optimized vs. Standard Automated Peritoneal Dialysis Regimens Study — OptiStAR

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms