Is Intercostal Tube Enough in Management of Empyema

Empyema Clinical Trial

Official title:

Is Intercostal Tube Enough in Management of Empyema

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06235359
• Other study ID #: empyema
• Status: Not yet recruiting
• Phase: N/A
• Start date: March 2024
• Est. completion date: December 2026

Study information

• Verified date: January 2024
• Source: Assiut University
• Contact: Islam abdelfatah, resident
• Phone: 01024984239
• Email: Islam.abdelfatah.097[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Is intercostal tube enough in management of empyema ?

Description:

Empyema refers to presence of pus in the pleural space -Causes Primary: bacterial Pneumonia (staph aureus, strept pneumonia , H.influenza) , TB

Secondry :

PostTraumati postoperative :open heart , esophageal, mediastinum , lung rupture of lung absess

-pathophysiology and stages During an inflammatory process such as pneumonia, there is an increase in fluid production in the pleural cavity known as the exudate stage. As the disease progresses microorganisms, usually bacteria, can colonize the fluid and generated an empyema. This fluid is characterized by elevated lactate dehydrogenase, proteins, neutrophils, and dead cells. Macroscopically is a thick opaque fluid found in the fibrinopurulent stage. After the resolution of the infection and as a consequence of the inflammation, there is a process of fibrosis that can lead to restriction of the lung parenchyma which is stage of chronic organization

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: December 2026
• Est. primary completion date: November 2026
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• patients admitted to Assuit university Hospital and diagnosed with empyema

Exclusion Criteria:

• Patient diagnosed with Post-operative empyema

• Patient diagnosed with post traumatic empyema

• Patient diagnosed with Bronchopleural fistula

• Patient diagnosed with TB

Related Conditions & MeSH terms

• Empyema

Intervention

Device:
• intercostal tube
A chest tube is a hollow, flexible tube placed into the chest. It acts as a drain. Chest tubes drain blood, fluid, or air from around your lungs, heart, or esophagus. The tube around your lung is placed between your ribs and into the space between the inner lining and the outer lining of your chest cavity. This is called the pleural space. It allows your lungs to fully expand.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (1)

Ali I, Unruh H. Management of empyema thoracis. Ann Thorac Surg. 1990 Sep;50(3):355-9. doi: 10.1016/0003-4975(90)90474-k. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	To find best way to drain the pus in the pleural space	To find best way to drain the pus in the pleural space	baseline