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NCT00144950 Clinical Trial

Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema

Empyema Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00144950
Other study ID # 02AR04
Secondary ID
Status Completed
Phase Phase 1
First received September 2, 2005
Last updated September 2, 2005

Study information
Verified date September 2005
Source Institute of Child Health
Contact n/a
Is FDA regulated No
Health authority United Kingdom: Research Ethics Committee
Study type Interventional

Clinical Trial Summary

This study will compare VATS versus chest drain insertion and urokinase in the treatment of childhood empema by a randomised prospective study.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group N/A to 16 Years
Eligibility Inclusion Criteria:

- patients under the age of 16 referred to GOSH for management of empyema

Exclusion Criteria:

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• insertion of a chest drain with urokinase instillation

Procedure:
• primary video-assisted thorascopic surgery

Locations
Country Name City State
United Kingdom Great Ormond Street Hospital London

Sponsors (1)
Lead Sponsor Collaborator
Institute of Child Health

Country where clinical trial is conducted

United Kingdom, 

Outcome
Type Measure Description Time frame Safety issue
Primary length of hospital stay
Secondary radiological changes at follow up
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