Management Standard of Bone Marrow Infusion in Acute and Critical Patients

Emergency Patients Clinical Trial

Official title:

Application Value of Precision Management Standard of Bone Marrow Infusion in Acute and Critical Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04951596
• Other study ID #: 2020-170
• Status: Recruiting
• Start date: July 1, 2020
• Est. completion date: December 31, 2022

Study information

• Verified date: January 2021
• Source: Second Affiliated Hospital, School of Medicine, Zhejiang University
• Contact: minfei yang
• Phone: +86 13757118252
• Email: 2200056[@]zju.edu.cn
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

As the spike in the number and severity of patients with critical patients, then quickly effective transfusion treatment demand becomes more and more serious, and the pattern of infusion pathways have traditionally used already can not adapt to this change, therefore, an urgent need to establish a set of is in line with international standards and accord with the situation of our country is simple, effective and scientific accuracy of IO management solution. In order to ensure the safety of the treatment of acute and critical patients, and in the province and even domestic experts recognized and promoted the application.

Description:

1. Investigate the current situation of infusion treatment for critical and critical patients in two hospitals in the province, the cognition of medical staff in critical and critical units on IO, IO training and assessment, and continuous quality improvement, etc. A comprehensive understanding of the needs of medical staff in the acute critical care unit for the refined IO management standard, including the analysis of the application of the standard in some hospitals.

2. Clarify and refine the contents of relevant indexes of IO management standards to form a standardized, scientific, unified and simple way to quickly judge difficult vessels. Defining the appropriate infusion access, infusion tool, puncture site, infusion speed, infusion effect, patient outcome, complications, indications, contraindication, infusion risk management, relevant personnel training and assessment, and continuous quality improvement as indexes.

3. On the basis of the standards of existing guidelines, a reasonable observation time range and the number of puncture times consistent with the first infusion puncture were established.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: December 31, 2022
• Est. primary completion date: December 31, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 1.Emergency medical staffMore than two years of critical work experience 2.Volunteer to participate in research

Exclusion Criteria:

• Patients who have neurological disease

Related Conditions & MeSH terms

• Emergencies
• Emergency Patients

Intervention

Other:
• Investigate the current situation
Investigate the current situation of infusion treatment for acute and critical patients in 2 hospitals in the province

Locations

Country	Name	City	State
China	2nd Affiliated Hospital, School of Medicine, Zhejiang University, China	Hangzhou	Zhejiang
China	2nd Affiliated Hospital, School of Medicine, Zhejiang University, China	Hanzhou	Zhejiang

Sponsors (1)

Lead Sponsor	Collaborator
Second Affiliated Hospital, School of Medicine, Zhejiang University

Country where clinical trial is conducted

China, 

References & Publications (4)

Link MS, Berkow LC, Kudenchuk PJ, Halperin HR, Hess EP, Moitra VK, Neumar RW, O'Neil BJ, Paxton JH, Silvers SM, White RD, Yannopoulos D, Donnino MW. Part 7: Adult Advanced Cardiovascular Life Support: 2015 American Heart Association Guidelines Update for — View Citation

Voigt J, Waltzman M, Lottenberg L. Intraosseous vascular access for in-hospital emergency use: a systematic clinical review of the literature and analysis. Pediatr Emerg Care. 2012 Feb;28(2):185-99. doi: 10.1097/PEC.0b013e3182449edc. Review. — View Citation

Wampler D, Schwartz D, Shumaker J, Bolleter S, Beckett R, Manifold C. Paramedics successfully perform humeral EZ-IO intraosseous access in adult out-of-hospital cardiac arrest patients. Am J Emerg Med. 2012 Sep;30(7):1095-9. doi: 10.1016/j.ajem.2011.07.01 — View Citation

Whitney R, Langhan M. Vascular Access in Pediatric Patients in the Emergency Department: Types of Access, Indications, and Complications. Pediatr Emerg Med Pract. 2017 Jun;14(6):1-20. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	complications in patients with intraosseous infusion	The number of complications occurred in the bone marrow cavity was calculated	one and a half years
Primary	time of infufusion access establishment for patients	The time of catheterization for each bone marrow cavity puncture was recorded	one and a half years
Primary	Success rate of infusion access establishment	The success rate of establishing the infusion access was calculated	one and a half years