The Diagnostic Value of the First Clinical Impression of Patients Presenting to the Emergency Department (PREKEYDIA)

Emergencies Clinical Trial

Official title:

The Diagnostic Value of the First Clinical Impression of Patients Presenting to the Emergency Department

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05597059
• Other study ID #: PREKEYDIA
• Status: Completed
• Start date: September 1, 2019
• Est. completion date: February 1, 2021

Study information

• Verified date: October 2022
• Source: Kepler University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Finding a diagnosis for acutely ill patients places high demands on emergency medical personnel. While anamnesis and clinical examination provide initial indications and allow a tentative diagnosis, both laboratory chemistry and imaging tests are used to confirm (or exclude) the tentative diagnosis. The more precise and targeted the additional laboratory chemical or radiological diagnosis, the more quickly and economically the causal treatment of the emergency patient can be initiated.

One examination modality, which in addition to the medical history and clinical examination, could quickly provide information about the condition of the patient, their clinical picture and severity of illness, is the first clinical impression of the patient (so-called "first impression" or "end-of-bed view"). This describes the first sensory impression that the medical staff gathers from a patient. This includes visual (e.g., facial expression, gait, breathing), auditory (e.g., voice pitch, shortness of breath when speaking), and olfactory (e.g., smell of exhaled air, body odor) impressions. Clinical practice shows that a great deal of important additional information can be gathered through this first clinical impression, which, together with the history and clinical examination of the emergency patient, provides valuable clues to the underlying condition.

To date, however, only scattered data and study results exist in the medical literature on the value of the first clinical impression in the care of emergency patients. In the present prospective observational study, the study attempts to evaluate the predictive value of the first clinical impression in identifying a leading symptom and other important clinical parameters.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1506
• Est. completion date: February 1, 2021
• Est. primary completion date: February 28, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients presenting to the emergency department between 2019-09-01 and 2020-02-28.

Exclusion Criteria:

• None.

Related Conditions & MeSH terms

• Emergencies

Intervention

Diagnostic Test:
• Machine Learning Prediction
Machine Learning Prediction

Locations

Country	Name	City	State
Austria	Kepler University Hospital	Linz	Upper Austria

Sponsors (1)

Lead Sponsor	Collaborator
Kepler University Hospital

Country where clinical trial is conducted

Austria, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	AUROC for Classification of Shortness of Breath	AUROC for Classification of Shortness of Breath	2019-09-01 to 2020-02-28
Primary	AUROC for Classification of Extremity Pathologies	AUROC for Classification of Extremity Pathologies	2019-09-01 to 2020-02-28
Primary	AUROC for Classification of Abdominal Pain	AUROC for Classification of Abdominal Pain	2019-09-01 to 2020-02-28
Primary	AUROC for Classification of Urological Pathologies	AUROC for Classification of Urological Pathologies	2019-09-01 to 2020-02-28
Primary	AUROC for Classification of Chest Pain	AUROC for Classification of Chest Pain	2019-09-01 to 2020-02-28
Primary	AUROC for Classification of Back Pain	AUROC for Classification of Back Pain	2019-09-01 to 2020-02-28
Secondary	AUROC for Classification of Hospital Admission	AUROC for Classification of Hospital Admission	2019-09-01 to 2020-02-28
Secondary	Confusion Matrix	Confusion Matrix Results: true positives, true negatives, false positive, false negatives and values calculated from these results.	2019-09-01 to 2020-02-28
Secondary	Descriptive Statistics	Descriptive Statistics (e. g. age in years)	2019-09-01 to 2020-02-28