Select Embryos by Time-lapse System for Single Embryo Transfer

Embryo Clinical Trial

— SETLSSET  

Official title:

Study Embryos of IVF by Time-lapse System

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT02313311
• Other study ID #: LJ201102-BK20141087-BL2014003
• Secondary ID: LJ201102
• Status: Enrolling by invitation
• Phase: N/A
• First received: December 7, 2014
• Last updated: December 7, 2014
• Start date: October 2013
• Est. completion date: December 2015

Study information

• Verified date: December 2014
• Source: Nanjing University
• Contact: n/a
• Is FDA regulated: No
• Health authority: China: Ethics Committee
• Study type: Observational

Clinical Trial Summary

The objective of this study is to establish a hierarchical embryo selection process by using the time-lapse imaging (TLI), combining the embryo cleavage patterns and timing parameters.

Description:

The embryos of patients undergoing in vitro fertilization (IVF) treatment is cultured to blastocyst stage and observed by TLI. The association of embryo cleavage patterns/timing parameters and good-quality blastocyst rates are evaluated by logistic regression and to establish a hierarchical embryo selection. The value of the selection process is assess by single embryo transfer (SET) on Day 3.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 500
• Est. completion date: December 2015
• Est. primary completion date: December 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Women undergoing assistant reproduction treatment

Exclusion Criteria:

• Oocyte donation cycles

Study Design

Observational Model: Cohort

Related Conditions & MeSH terms

• Embryo

Intervention

Other:
• time-lapse imaging
Embryos are observed using time-lapse imaging (Primo Vision®). It is an incubator with a compact, sealed, and digitally inverted camera unit which can automatically acquire images.The system can record the actual developmental stage of the embryos, all the recorded images can be saved to be analyzed later using a special software program.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Li-jun Ding

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	good-quality blastocyst rate		6 days post insemination	Yes